SH2D5 Antibody - #DF4498

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产品: SH2D5 抗体
货号: DF4498
描述: Rabbit polyclonal antibody to SH2D5
应用: WB IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Bovine, Horse, Sheep, Rabbit, Dog
蛋白号: Q6ZV89
RRID: AB_2836849

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
SH2D5 Antibody detects endogenous levels of total SH2D5.
RRID:
AB_2836849
引用格式: Affinity Biosciences Cat# DF4498, RRID:AB_2836849.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FLJ41242; FLJ41847; FLJ42879; SH2 domain containing 5; SH2 domain-containing protein 5; SH2D5; SH2D5_HUMAN;

抗原和靶标

免疫原:

A synthesized peptide derived from human SH2D5, corresponding to a region within C-terminal amino acids.

基因/基因ID:
SH2D5(400745)

文献引用

1). SH2D5 promotes lung adenocarcinoma cell metastasis and triggers EMT via activating AKT signaling pathway. PloS one, 2024 (PubMed: 39775732) [IF=3.7]

Application: WB    Species: human    Sample: 16HBE and LUAD cell

Fig 1. High SH2D5 expression in lung adenocarcinoma (LUAD) is associated with poor prognosis. (A) The expression level of SH2D5 in 539 SH2D5 samples and 59 normal samples in The Cancer Genome Atlas (TCGA) database. (B) The expression of SH2D5 in 58 paired TCGA tumors and corresponding adjacent noncancerous tissues. (C, D) Overall survival and disease specific survival in low and high SH2D5 expression patients in TGCA cohort. (E, F) Western blot analysis of SH2D5 expression levels in 16HBE and LUAD cell lines.

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