IQGAP3 Antibody - #DF4389

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产品: IQGAP3 抗体
货号: DF4389
描述: Rabbit polyclonal antibody to IQGAP3
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 180 KD; 185kD(Calculated).
蛋白号: Q86VI3
RRID: AB_2836744

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 100ul RMB¥ 2300 现货
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货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Zebrafish(91%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(91%), Xenopus(100%)
克隆:
Polyclonal
特异性:
IQGAP3 Antibody detects endogenous levels of total IQGAP3.
RRID:
AB_2836744
引用格式: Affinity Biosciences Cat# DF4389, RRID:AB_2836744.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

IQ motif containing GTPase activating protein 3; IQGA3_HUMAN; IQGAP 3; IQGAP3; MGC10170; MGC10831; MGC1947; OTTHUMP00000031854; OTTHUMP00000031855; Ras GTPase activating like protein IQGAP3; Ras GTPase-activating-like protein IQGAP3;

抗原和靶标

免疫原:
Uniprot:

Q86VI3(IQGA3_HUMAN) >>Visit HPA database.

基因/基因ID:
IQGAP3(128239)
序列:
MERRAAGPGWAAYERLTAEEMDEQRRQNVAYQYLCRLEEAKRWMEACLKEELPSPVELEESLRNGVLLAKLGHCFAPSVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAIAHIGLPSTFFPETTDIYDKKNMPRVVYCIHALSLFLFRLGLAPQIHDLYGKVKFTAEELSNMASELAKYGLQLPAFSKIGGILANELSVDEAAVHAAVLAINEAVERGVVEDTLAALQNPSALLENLREPLAAVYQEMLAQAKMEKAANARNHDDRESQDIYDHYLTQAEIQGNINHVNVHGALEVVDDALERQSPEALLKALQDPALALRGVRRDFADWYLEQLNSDREQKAQELGLVELLEKEEVQAGVAAANTKGDQEQAMLHAVQRINKAIRRRVAADTVKELMCPEAQLPPVYPVASSMYQLELAVLQQQQGELGQEELFVAVEMLSAVVLINRALEARDASGFWSSLVNPATGLAEVEGENAQRYFDALLKLRQERGMGEDFLSWNDLQATVSQVNAQTQEETDRVLAVSLINEALDKGSPEKTLSALLLPAAGLDDVSLPVAPRYHLLLVAAKRQKAQVTGDPGAVLWLEEIRQGVVRANQDTNTAQRMALGVAAINQAIKEGKAAQTERVLRNPAVALRGVVPDCANGYQRALESAMAKKQRPADTAFWVQHDMKDGTAYYFHLQTFQGIWEQPPGCPLNTSHLTREEIQSAVTKVTAAYDRQQLWKANVGFVIQLQARLRGFLVRQKFAEHSHFLRTWLPAVIKIQAHWRGYRQRKIYLEWLQYFKANLDAIIKIQAWARMWAARRQYLRRLHYFQKNVNSIVKIQAFFRARKAQDDYRILVHAPHPPLSVVRRFAHLLNQSQQDFLAEAELLKLQEEVVRKIRSNQQLEQDLNIMDIKIGLLVKNRITLQEVVSHCKKLTKRNKEQLSDMMVLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPIYLAKLIFQMPQNKTTKFMEAVIFSLYNYASSRREAYLLLQLFKTALQEEIKSKVEQPQDVVTGNPTVVRLVVRFYRNGRGQSALQEILGKVIQDVLEDKVLSVHTDPVHLYKNWINQTEAQTGQRSHLPYDVTPEQALSHPEVQRRLDIALRNLLAMTDKFLLAITSSVDQIPYGMRYVAKVLKATLAEKFPDATDSEVYKVVGNLLYYRFLNPAVVAPDAFDIVAMAAGGALAAPQRHALGAVAQLLQHAAAGKAFSGQSQHLRVLNDYLEETHLKFRKFIHRACQVPEPEERFAVDEYSDMVAVAKPMVYITVGELVNTHRLLLEHQDCIAPDHQDPLHELLEDLGELPTIPDLIGESIAADGHTDLSKLEVSLTLTNKFEGLEADADDSNTRSLLLSTKQLLADIIQFHPGDTLKEILSLSASREQEAAHKQLMSRRQACTAQTPEPLRRHRSLTAHSLLPLAEKQRRVLRNLRRLEALGLVSARNGYQGLVDELAKDIRNQHRHRHRRKAELVKLQATLQGLSTKTTFYEEQGDYYSQYIRACLDHLAPDSKSSGKGKKQPSLHYTAAQLLEKGVLVEIEDLPASHFRNVIFDITPGDEAGKFEVNAKFLGVDMERFQLHYQDLLQLQYEGVAVMKLFNKAKVNVNLLIFLLNKKFLRK

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Rabbit
100
Zebrafish
91
Chicken
91
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q86VI3 作为底物

Site PTM Type Enzyme
Y13 Phosphorylation
K70 Ubiquitination
K83 Ubiquitination
Y140 Phosphorylation
K164 Ubiquitination
K166 Ubiquitination
T168 Phosphorylation
S201 Phosphorylation
K314 Ubiquitination
R324 Methylation
K345 Ubiquitination
K357 Ubiquitination
K386 Ubiquitination
K398 Methylation
K537 Ubiquitination
S539 Phosphorylation
K542 Ubiquitination
K573 Ubiquitination
K576 Ubiquitination
T628 Phosphorylation
K660 Ubiquitination
K876 Ubiquitination
K907 Ubiquitination
K938 Acetylation
K943 Ubiquitination
K947 Acetylation
K949 Acetylation
K981 Ubiquitination
K1011 Acetylation
K1011 Ubiquitination
T1012 Phosphorylation
K1019 Ubiquitination
K1021 Ubiquitination
K1067 Ubiquitination
K1080 Acetylation
K1080 Ubiquitination
Y1098 Phosphorylation
T1101 Phosphorylation
T1134 Phosphorylation
S1135 Phosphorylation
S1136 Phosphorylation
K1152 Ubiquitination
K1158 Ubiquitination
K1169 Ubiquitination
K1245 Ubiquitination
Y1268 Phosphorylation
S1269 Phosphorylation
T1289 Phosphorylation
S1360 Phosphorylation
T1362 Phosphorylation
K1370 Ubiquitination
K1402 Ubiquitination
T1412 Phosphorylation
T1415 Phosphorylation
S1424 Phosphorylation
T1426 Phosphorylation
S1429 Phosphorylation
K1436 Ubiquitination
S1509 Phosphorylation
S1523 Phosphorylation
K1524 Ubiquitination
S1525 Phosphorylation
S1526 Phosphorylation
K1531 Ubiquitination
Y1537 Phosphorylation
T1538 Phosphorylation
K1545 Ubiquitination

研究背景

研究领域

· Cellular Processes > Cell motility > Regulation of actin cytoskeleton.   (View pathway)

文献引用

1). IQGAP3 promotes the progression of glioma as an immune and prognostic marker. Oncology research, 2024 (PubMed: 38560572) [IF=2.0]

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