| 产品: | NCOA7 抗体 |
| 货号: | DF4256 |
| 描述: | Rabbit polyclonal antibody to NCOA7 |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 预测: | Rabbit |
| 分子量: | 106 KD; 106kD(Calculated). |
| 蛋白号: | Q8NI08 |
| RRID: | AB_2836607 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4256, RRID:AB_2836607.
展开/折叠
140 kDa estrogen receptor associated protein; 9030406N13Rik; dJ187J11.3; ERAP140; ESNA1; Estrogen nuclear receptor coactivator 1; FLJ45605; MGC88425; Nbla00052; Nbla10993; Nuclear receptor coactivator 7; RGD1566426;
抗原和靶标
Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.
- Q8NI08 NCOA7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDTKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAGNQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPQDLCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVPLEKSTGHTPTKPSGSSVSEKLKKLDSSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDVELKGALDLETCEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQVSENLQKTELSDGKSIEPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNSSTEANVIKEALDSSLESTLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDEEVLPVLRPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWAFD
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q8NI08 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S13 | Phosphorylation | Uniprot | |
| T38 | Phosphorylation | Uniprot | |
| T40 | Phosphorylation | Uniprot | |
| Y87 | Phosphorylation | Uniprot | |
| Y88 | Phosphorylation | Uniprot | |
| S89 | Phosphorylation | Uniprot | |
| K109 | Ubiquitination | Uniprot | |
| T134 | Phosphorylation | Uniprot | |
| S162 | Phosphorylation | Uniprot | |
| T166 | Phosphorylation | Uniprot | |
| S170 | Phosphorylation | Uniprot | |
| S171 | Phosphorylation | Uniprot | |
| S173 | Phosphorylation | Uniprot | |
| T177 | Phosphorylation | Uniprot | |
| S179 | Phosphorylation | Uniprot | |
| S181 | Phosphorylation | Uniprot | |
| S182 | Phosphorylation | Uniprot | |
| S183 | Phosphorylation | Uniprot | |
| Y187 | Phosphorylation | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| S209 | Phosphorylation | Uniprot | |
| T210 | Phosphorylation | Uniprot | |
| S211 | Phosphorylation | Uniprot | |
| K220 | Ubiquitination | Uniprot | |
| K290 | Ubiquitination | Uniprot | |
| K317 | Ubiquitination | Uniprot | |
| T355 | Phosphorylation | Uniprot | |
| T358 | Phosphorylation | Uniprot | |
| S363 | Phosphorylation | Uniprot | |
| S365 | Phosphorylation | Uniprot | |
| S376 | Phosphorylation | Uniprot | |
| T380 | Phosphorylation | Uniprot | |
| S384 | Phosphorylation | Uniprot | |
| S391 | Phosphorylation | Uniprot | |
| S395 | Phosphorylation | Uniprot | |
| T435 | Phosphorylation | Uniprot | |
| S441 | Phosphorylation | Uniprot | |
| S500 | Phosphorylation | Uniprot | |
| S502 | Phosphorylation | Uniprot | |
| K519 | Acetylation | Uniprot | |
| K519 | Ubiquitination | Uniprot | |
| Y525 | Phosphorylation | Uniprot | |
| Y526 | Phosphorylation | Uniprot | |
| K531 | Ubiquitination | Uniprot | |
| K542 | Ubiquitination | Uniprot | |
| S565 | Phosphorylation | Uniprot | |
| S596 | Phosphorylation | Uniprot | |
| S609 | Phosphorylation | Uniprot | |
| S670 | Phosphorylation | Uniprot | |
| Y691 | Phosphorylation | Uniprot | |
| K756 | Ubiquitination | Uniprot | |
| S760 | Phosphorylation | Uniprot | |
| T761 | Phosphorylation | Uniprot | |
| S763 | Phosphorylation | Uniprot | |
| Y765 | Phosphorylation | Uniprot | |
| K818 | Ubiquitination | Uniprot | |
| K823 | Ubiquitination | Uniprot | |
| S918 | Phosphorylation | Uniprot | |
| T919 | Phosphorylation | Uniprot | |
| S926 | Phosphorylation | Uniprot | |
| K927 | Ubiquitination | Uniprot |
研究背景
Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.
Nucleus.
Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.
Interacts with ESR1, ESR2A, ESR2B, THRB, PPARG and RARA in a ligand-inducible manner. Interacts with the heterodimer AHR-ARNT.
Belongs to the OXR1 family.
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