CYB5R1 Antibody - #DF4211

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产品: CYB5R1 抗体
货号: DF4211
描述: Rabbit polyclonal antibody to CYB5R1
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 34 KD; 34kD(Calculated).
蛋白号: Q9UHQ9
RRID: AB_2836562

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Zebrafish(90%), Bovine(82%), Horse(91%), Sheep(82%), Rabbit(100%), Dog(100%)
克隆:
Polyclonal
特异性:
CYB5R1 Antibody detects endogenous levels of total CYB5R1.
RRID:
AB_2836562
引用格式: Affinity Biosciences Cat# DF4211, RRID:AB_2836562.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

b5R.1; B5R1; B5R2; CYB5R1; Cytochrome b5 reductase 1; EC 1.6.2.2; Humb5R2; NAD; NAD(P)H:quinone oxidoreductase type 3 polypeptide A2; NAD(P)H:quinone oxidoreductase type 3, polypeptide A2; NADH cytochrome b5 reductase 1; NADH-cytochrome b5 reductase 1; NB5R1_HUMAN; NQO3A2; UNQ3049/PRO9865;

抗原和靶标

免疫原:
Uniprot:

Q9UHQ9(NB5R1_HUMAN) >>Visit HPA database.

基因/基因ID:
CYB5R1(51706)
表达:
Q9UHQ9 NB5R1_HUMAN:

Widely expressed.

序列:
MGIQTSPVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTLLDPNEKYLLRLLDKTTVSHNTKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLWFTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGYSQKMRFTY

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Dog
100
Rabbit
100
Horse
91
Zebrafish
90
Bovine
82
Sheep
82
Xenopus
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9UHQ9 作为底物

Site PTM Type Enzyme
K54 Ubiquitination
T56 Phosphorylation
K62 Ubiquitination
K81 Ubiquitination
Y84 Phosphorylation
K119 Ubiquitination
K124 Ubiquitination
K130 Methylation
K130 Ubiquitination
K139 Methylation
K139 Ubiquitination
S150 Phosphorylation
K167 Acetylation
K167 Ubiquitination
S169 Phosphorylation
K178 Ubiquitination
T186 Phosphorylation
T189 Phosphorylation
K200 Ubiquitination
K218 Ubiquitination
K248 Ubiquitination
K254 Ubiquitination
T258 Phosphorylation
K300 Ubiquitination

研究背景

功能:

NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.

细胞定位:

Membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Widely expressed.

蛋白家族:

Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

研究领域

· Metabolism > Carbohydrate metabolism > Amino sugar and nucleotide sugar metabolism.

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