MRC1/CD206 Antibody - #DF4149

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产品: MRC1/CD206 抗体
货号: DF4149
描述: Rabbit polyclonal antibody to MRC1/CD206
应用: WB IHC IF/ICC
文献验证: WB, IHC, IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
蛋白号: P22897
RRID: AB_2836514

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   规格 价格 库存
 50ul RMB¥ 1000 1250 现货
 100ul RMB¥ 1840 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
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说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IHC 1:50-1:100, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
MRC1 Antibody detects endogenous levels of total MRC1.
RRID:
AB_2836514
引用格式: Affinity Biosciences Cat# DF4149, RRID:AB_2836514.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

bA541I19.1; C type lectin domain family 13 member D; C-type lectin domain family 13 member D; CD 206; CD206; CD206 antigen; CLEC13D; CLEC13DL; Macrophage mannose receptor 1; Macrophage mannose receptor 1 like protein 1; Macrophage mannose receptor; Mannose receptor C type 1; Mannose receptor C type 1 like 1; MMR; MRC 1; MRC1; MRC1_HUMAN; MRC1L1; OTTHUMP00000045206;

抗原和靶标

免疫原:

A synthesized peptide derived from human MRC1, corresponding to a region within the internal amino acids.

基因/基因ID:
MRC1(4360)

研究领域

· Cellular Processes > Transport and catabolism > Phagosome.   (View pathway)

· Human Diseases > Infectious diseases: Bacterial > Tuberculosis.

文献引用

1). Molecular co-assembled strategy tuning protein conformation for cartilage regeneration. Nature communications, 2024 (PubMed: 38374253) [IF=16.6]
2). Nonswellable Hydrogel Patch with Tissue-Mimetic Mechanical Characteristics Remodeling In Vivo Microenvironment for Effective Adhesion Prevention. ACS nano, 2024 (PubMed: 38932673) [IF=15.8]
3). Antibacterial Peptides-Produced Cell Hydrogel Eliminates Intracellular Pathogens and Remodels Immune Microenvironment for Osteomyelitis Therapy. ACS nano, 2025 (PubMed: 40336314) [IF=15.8]
4). An Antigen-Free Nanovaccine-Enabled Holo-Immunotherapy for Establishing Robust Memory Immune Tolerance in Autoimmune Diseases. ACS nano, 2025 (PubMed: 40944643) [IF=15.8]
5). The Thyroid Hormone Analog GC-1 Mitigates Acute Lung Injury by Inhibiting M1 Macrophage Polarization. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024 (PubMed: 39373388) [IF=15.1]
6). Interplay between lipid dysregulation and ferroptosis in chondrocytes and the targeted therapy effect of metformin on osteoarthritis. Journal of advanced research, 2025 (PubMed: 38621621) [IF=11.4]
7). Custom-Made Ce-Mn Bimetallic Nanozyme for the Treatment of Intervertebral Disc Degeneration by Inhibiting Oxidative Stress and Modulating Macrophage M1/M2 Polarization. Biomaterials research, 2024 (PubMed: 39717477) [IF=11.3]
8). Manganese-Based Polyoxometalate Nanozyme-Metformin Co-functionalized Hydrogel Promotes Diabetic Wound Regeneration by Enhancing Phagocyte Efferocytosis. Research (Washington, D.C.), 2025 (PubMed: 41395249) [IF=11.0]

Application: IF/ICC    Species: Mouse    Sample:

Fig. 6. Regulation of efferocytosis in DC and macrophages by GPP-M@L. (A) Efferocytosis of DCs following treatment with different hydrogel groups as detected by conjugate product reaction. Scale bar, 50 μm. (B) Quantitative analysis of conjugate expression from (A). (C) Immunofluorescence images showing the expression of iNOS (green) and CD206 (red) in macrophages treated with different conditioned media. Nuclei were counterstained with DAPI (blue). Scale bar, 20 μm. (D) Quantitative analysis of iNOS expression. (E) Quantitative analysis of CD206 expression. (F) Efferocytosis of macrophages following treatment with different conditioned media as detected by conjugate product reaction. Scale bar, 50 μm. (G) Quantitative analysis of conjugate expression from (F). All values are presented as mean ± SD; *P < 0.05, **P < 0.01; P ≥ 0.05 is considered nonsignificant (NS). The control group represents hyperglycemia.
9). Honokiol@ PF127 crosslinked hyaluronate-based hydrogel for promoting wound healing by regulating macrophage polarization. Carbohydrate Polymers, 2023 (PubMed: 36657865) [IF=10.7]
10). Plasma Membrane-Derived Biomimetic Apoptotic Nanovesicles Targeting Inflammation and Cartilage Degeneration for Osteoarthritis. Small methods, 2024 (PubMed: 39036830) [IF=10.7]
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