产品: LIPI 抗体
货号: DF4141
描述: Rabbit polyclonal antibody to LIPI
应用: WB IHC IF/ICC
反应: Human
分子量: 53 KD; 53kD(Calculated).
蛋白号: Q6XZB0
RRID: AB_2836506

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
LIPI Antibody detects endogenous levels of total LIPI.
RRID:
AB_2836506
引用格式: Affinity Biosciences Cat# DF4141, RRID:AB_2836506.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Cancer/testis antigen 17; CT17; Lipase member I; LIPI; LIPI_HUMAN; LPD lipase; LPDL; Membrane-associated phosphatidic acid-selective phospholipase A1-beta; membrane-associated phospholipase A1 beta 7B+; membrane-associated phospholipase A1 beta deltaE2-3; membrane-associated phospholipase A1 beta deltaE5; membrane-associated phospholipase A1 beta deltaE6.1; membrane-associated phospholipase A1 beta deltaE7.2; membrane-associated phospholipase A1 beta deltaE8-9; membrane-associated phospholipase A1 beta fl; mPA-PLA1 beta; PLA1C; PRED5;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q6XZB0 LIPI_HUMAN:

Expressed in testis. Expressed exclusively at the connecting piece of the sperm.

序列:
MRVYIFLCLMCWVRSDNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNISSIGLTYFQSSNLQCSTCTYKIQSLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPKNT

研究背景

功能:

Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).

细胞定位:

Membrane. Secreted.
Note: May associate with lipid draft.

Membrane. Secreted.
Note: May associate with lipid draft.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in testis. Expressed exclusively at the connecting piece of the sperm.

亚基结构:

Interacts with heparin with a high affinity.

蛋白家族:

Belongs to the AB hydrolase superfamily. Lipase family.

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