产品: KCNN4 抗体
货号: DF4132
描述: Rabbit polyclonal antibody to KCNN4
应用: WB IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Horse, Sheep, Rabbit, Dog
蛋白号: O15554
RRID: AB_2836497

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 50ul RMB¥ 1250 现货
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 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
KCNN4 Antibody detects endogenous levels of total KCNN4.
RRID:
AB_2836497
引用格式: Affinity Biosciences Cat# DF4132, RRID:AB_2836497.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

DHS2; hIKCa1; hKCa4; hSK4; IK; IK1; IKCa1; Intermediate conductance calcium activated potassium channel protein 4; Intermediate conductance calcium-activated potassium channel protein 4; KCa3.1; KCa4; KCNN 4; Kcnn4; KCNN4_HUMAN; Potassium calcium activated channel subfamily N member 4; Potassium intermediate/small conductance calcium activated channel, subfamily N, member 4; Putative Gardos channel; SK4; SKCa 4; SKCa4;

抗原和靶标

免疫原:

A synthesized peptide derived from human KCNN4, corresponding to a region within C-terminal amino acids.

基因/基因ID:

研究领域

· Organismal Systems > Endocrine system > Insulin secretion.   (View pathway)

· Organismal Systems > Digestive system > Salivary secretion.

· Organismal Systems > Digestive system > Protein digestion and absorption.

文献引用

1). A prospective diagnostic and prognostic biomarker for hepatocellular carcinoma that functions in glucose metabolism regulation: Solute carrier family 37 member 3. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2023 (PubMed: 36773462) [IF=4.2]

2). KCNN4 is a potential prognostic marker and critical factor affecting the immune status of the tumor microenvironment in kidney renal clear cell carcinoma. Translational Andrology and Urology, 2021 (PubMed: 34295732) [IF=1.9]

Application: WB    Species: Human    Sample: kidney renal clear cell

Figure 13 Expression of KCNN4 increased in KIRC samples. (A) Expression of KCNN4 in KIRC samples and normal adjacent non-tumor controls were assessed by qPCR (*P<0.05). (B,C) Representative blots and quantification results of western blot showed that expression of the KCNN4 protein in KIRC was significantly higher than controls (*P<0.05). KIRC, kidney renal clear cell carcinoma.

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