产品: Myoglobin 抗体
货号: BF0424
描述: Mouse monoclonal antibody to Myoglobin
应用: WB IHC ELISA
反应: Human
分子量: 17kDa.; 17kD(Calculated).
蛋白号: P02144
RRID: AB_2833582

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   规格 价格 库存
 50ul RMB¥ 1800 现货
 100ul RMB¥ 2800 现货

货期: 当天发货

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产品描述

来源:
Mouse
应用:
ELISA 1:10000, WB 1:500-1:2000, IHC 1:200-1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFB1557]
特异性:
Myoglobin antibody detects endogenous levels of total Myoglobin.
RRID:
AB_2833582
引用格式: Affinity Biosciences Cat# BF0424, RRID:AB_2833582.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

MB; MGC13548; MYG_HUMAN; Myoglobin; PVALB;

抗原和靶标

免疫原:

Purified recombinant fragment of human Myoglobin expressed in E. Coli.

Uniprot:
基因/基因ID:
描述:
Myoglobin (MB), with 154-amino acid protein (about 17kDa), is a member of the globin superfamily and expression of myoglobin is highest in skeletal and cardiac muscle. Functionally, myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia. Myoglobin is also thought to buffer intracellular O2 concentration when muscle activity increases and to facilitate intracellular O2 diffusion by providing a parallel path that augments simple diffusion of dissolved O2. Furthermore, myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.
序列:
MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG

翻译修饰 - P02144 作为底物

Site PTM Type Enzyme
S4 Phosphorylation
K17 Acetylation
K46 Acetylation
K48 Acetylation
K51 Acetylation
K57 Acetylation
S59 Phosphorylation
K63 Acetylation
K64 Acetylation
T68 Phosphorylation
T71 Phosphorylation
K78 Acetylation
Y104 Phosphorylation
S118 Phosphorylation
S145 Phosphorylation
Y147 Phosphorylation

研究背景

功能:

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

蛋白家族:

Belongs to the globin family.

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