GNL3L Antibody - #DF4113

>>奖励金 进行中>>
(2)   (2)  
产品: GNL3L 抗体
货号: DF4113
描述: Rabbit polyclonal antibody to GNL3L
应用: WB IF/ICC
文献验证: WB
反应: Human, Monkey
预测: Pig, Bovine, Horse, Rabbit, Dog
蛋白号: Q9NVN8
RRID: AB_2836404

浏览相似产品>>

   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

联系销售
相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Monkey
克隆:
Polyclonal
特异性:
GNL3L Antibody detects endogenous levels of total GNL3L.
RRID:
AB_2836404
引用格式: Affinity Biosciences Cat# DF4113, RRID:AB_2836404.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FLJ10613; Guanine nucleotide binding protein-like 3 (nucleolar)-like; novel GTPase; OTTHUMP00000023374;

抗原和靶标

免疫原:

A synthesized peptide derived from human GNL3L, corresponding to a region within N-terminal amino acids.

基因/基因ID:
GNL3L(54552)

研究领域

· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.

文献引用

1). The GNL3L-MDM2 Interaction Drives Esophageal Squamous Cell Carcinoma Progression. Cancer medicine, 2025 (PubMed: 40856423) [IF=2.9]

Application: WB    Species: human    Sample:

FIGURE 1 Expression of GNL3L in esophageal cancer (EC) and the cell line model of GNL3L knockdown. (a) GNL3L expression was analyzed in EC tumor tissues (n = 182) and normal esophageal tissues (n = 286) using the GEPIA database. (b) Kaplan–Meier analysis of survival rates between patients with EC and low expression of GNL3L (n = 138) vs. high expression of GNL3L (n = 46). In addition to the expression of GNL3L, the survival rate was also related to tumor grade. The patient cohort was obtained from the gene information of TCGA Esophageal cancer datasets downloaded from the UALCAN website. (c) Immunohistochemistry was performed to detect differential expression of GNL3L protein in an esophageal squamous cell carcinoma (ESCC) specimen. (d) qRT-PCR was used to detect GNL3L expression in ESCC cell lines (TE-1, KYSE-410, KYSE-30, and EC9706) and human normal esophageal epithelial cell line (HEEC). (e) The expression of GNL3L protein in ESCC cell lines and HEEC was assessed using western blotting (WB). (f) Efficiency of sh-GNL3L for GNL3L in TE-1 cells by qRT-PCR. (g) The protein expression of GNL3L in TE-1 cells. (NC: Negative control). (*p 
2). GNL3L promotes autophagy via regulating AMPK signaling in esophageal cancer cells. Medical oncology (Northwood, London, England), 2023 (PubMed: 38148364) [IF=2.8]

限制条款

产品的规格、报价、验证数据请以官网为准，官网链接：www.affbiotech.com | www.affbiotech.cn（简体中文）| www.affbiotech.jp（日本語）

产品的数据信息为Affinity所有，未经授权不得收集Affinity官网数据或资料用于商业用途，对抄袭产品数据的行为我们将保留诉诸法律的权利。

产品相关数据会因产品批次、产品检测情况随时调整，如您已订购该产品，请以订购时随货说明书为准，否则请以官网内容为准，官网内容有改动时恕不另行通知。

Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时，请您在Affinity官方渠道提交售后申请。

产品仅供科学研究使用。不用于诊断和治疗。 

产品未经授权不得转售。

Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.