GNAL Antibody - #DF4108

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产品: GNAL 抗体
货号: DF4108
描述: Rabbit polyclonal antibody to GNAL
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
蛋白号: P38405
RRID: AB_2836399

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
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说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
GNAL Antibody detects endogenous levels of total GNAL.
RRID:
AB_2836399
引用格式: Affinity Biosciences Cat# DF4108, RRID:AB_2836399.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

;Adenylate cyclase stimulating G alpha protein, olfactory type; Adenylate cyclase-stimulating G alpha protein; DYT25; G alpha olf; Gnal; GNAL_HUMAN; Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide, olfactory type; Guanine nucleotide binding protein G(olf) subunit alpha; Guanine nucleotide-binding protein G(olf) subunit alpha; olfactory type;

抗原和靶标

免疫原:

A synthesized peptide derived from human GNAL, corresponding to a region within the internal amino acids.

基因/基因ID:
GNAL(2774)

研究领域

· Environmental Information Processing > Signal transduction > Calcium signaling pathway.   (View pathway)

· Human Diseases > Neurodegenerative diseases > Parkinson's disease.

· Human Diseases > Infectious diseases: Parasitic > Chagas disease (American trypanosomiasis).

· Human Diseases > Infectious diseases: Parasitic > Amoebiasis.

· Organismal Systems > Nervous system > Dopaminergic synapse.

· Organismal Systems > Sensory system > Olfactory transduction.

文献引用

1). Long Mu Qing Xin mixture improves behavioral performance in spontaneously hypertensive rats (SHR/NCrl) by upregulating catecholamine neurotransmitters in prefrontal cortex and striatum via DRD1/cAMP/PKA-CREB signaling pathway. Frontiers in pharmacology, 2024 (PubMed: 39027341) [IF=5.6]

Application: WB    Species: Rat    Sample:

FIGURE 6 Effects of LMQXM on the relative expression of DRD1, Gαs, Gαolf, PKA, p-CREB, and BDNF proteins in rat PFC and striatum. (A) Relative expression of DRD1 proteins; (B) Relative expression of Gαs proteins; (C) Relative expression of Gαolf proteins; (D) Relative expression of PKA proteins; (E) Relative expression of p-CREB proteins; (F) Relative expression of BDNF proteins. (H) Western blot analysis images of each group of proteins in PFC; (G) Western blot analysis images of each group of proteins in striatum. Data are expressed as mean ± standard deviation, n = 3 for each group. Compared with the WKY group, # p < 0.05, ## p < 0.01, ### p < 0.001, compared with the SHR group, * p < 0.05, ** p < 0.01, *** p < 0.001 and compared with the LMQXM-MD group, ^ p < 0.05.
2). An integrative analysis based on multiple cell death patterns identifies an immunosuppressive subtype and establishes a prognostic signature in lower-grade glioma. Annals of medicine, 2024 (PubMed: 39387560) [IF=4.9]

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