产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4019, RRID:AB_2836379.
展开/折叠
E3 ubiquitin protein ligase MARCH3; E3 ubiquitin-protein ligase MARCH3; FLJ20096; March 3; MARCH III; MARCH-III; March3; MARH3_HUMAN; Membrane associated RING CH protein III; Membrane associated ring finger (C3HC4) 3; Membrane associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase; Membrane associated RING finger protein 3; Membrane-associated RING finger protein 3; Membrane-associated RING-CH protein III; MGC48332; RING finger protein 173; RNF173;
抗原和靶标
- Q86UD3 MARH3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTTSRCSHLPEVLPDCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAVDHLHFSSRLEAVGLIALTVALFTIYLFWTLVSFRYHCRLYNEWRRTNQRVILLIPKSVNVPSNQPSLLGLHSVKRNSKETVV
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Cytoplasmic vesicle membrane>Multi-pass membrane protein. Early endosome membrane>Multi-pass membrane protein.
Interacts with MARCHF2 and STX6.
The RING-CH-type zinc finger domain is required for E3 ligase activity.
限制条款
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