产品: CLIP4 抗体
货号: DF3879
描述: Rabbit polyclonal antibody to CLIP4
应用: WB IHC IF/ICC
文献验证: IHC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
蛋白号: Q8N3C7
RRID: AB_2836232

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
CLIP4 Antibody detects endogenous levels of total CLIP4.
RRID:
AB_2836232
引用格式: Affinity Biosciences Cat# DF3879, RRID:AB_2836232.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CAP GLY domain containing linker protein family member 4; CAP-Gly domain-containing linker protein 4; Clip4; CLIP4_HUMAN; Restin like 2; Restin-like protein 2; RSNL2;

抗原和靶标

免疫原:

A synthesized peptide derived from human CLIP4, corresponding to a region within the internal amino acids.

基因/基因ID:

文献引用

1). miR-135b-5p promotes gastric carcinogenesis by targeting CLIP4-mediated JAK2/STAT3 signal pathway. Cellular signalling, 2024 (PubMed: 39121973) [IF=4.4]

2). Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis. BMC cancer, 2025 (PubMed: 39920578) [IF=3.8]

Application: IHC    Species: human    Sample:

Fig. 1 Elevated CLIP4 expression correlates with poor prognosis in HCC patients. A The expression levels of CLIP4 were examined in 33 distinct types of cancer tissues alongside their corresponding adjacent tissues utilizing the TCGA database. B, C Unpaired (B) and paired samples (C) from the TCGA-LIHC dataset were used to analyze the mRNA expression of CLIP4 in liver cancer and normal tissues. D The relationship between CLIP4 expression and the OS of liver cancer patients was analyzed via the TCGA-LIHC dataset. E CLIP4 expression in different histological grade groups (TCGA). F, G Effects of CLIP4 expression on AFP level (F) and gender (G) (TCGA-LIHC). H Representative images of CLIP4 IHC staining intensity in liver cancer and adjacent tissues. I CLIP4 expression in HCC and adjacent nontumor tissues. J Effect of a history of hepatitis on CLIP4 expression. K, L IHC staining for CLIP4 in differentiation (K) and tumor size (L). M The OS of individuals with high expression (n = 19) or low expression (n = 14) of CLIP4 was analyzed via Kaplan‒Meier analysis

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