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| 产品: | CLIP3 抗体 |
| 货号: | DF3878 |
| 描述: | Rabbit polyclonal antibody to CLIP3 |
| 应用: | WB IF/ICC |
| 文献验证: | WB, IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 60 KD; 60kD(Calculated). |
| 蛋白号: | Q96DZ5 |
| RRID: | AB_2836231 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3878, RRID:AB_2836231.
展开/折叠
1500005P14Rik; AI844915; CAP GLY domain containing linker protein 3; CAP-Gly domain-containing linker protein 3; CLIP 170 related 59 kDa protein; CLIP-170-related 59 kDa protein; clip3; CLIP3_HUMAN; CLIPR 59; CLIPR-59; CLIPR59; Cytoplasmic linker protein 170 related 59 kDa protein; Cytoplasmic linker protein 170-related 59 kDa protein; Restin like 1; RSNL1;
抗原和靶标
- Q96DZ5 CLIP3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTKTDPAPMAPPPRGEEEEEEEEDEPVPEAPSPTQERRQKPVVHPSAPAPLPKDYAFTFFDPNDPACQEILFDPQTTIPELFAIVRQWVPQVQHKIDVIGNEILRRGCHVNDRDGLTDMTLLHYACKAGAHGVGDPAAAVRLSQQLLALGADVTLRSRWTNMNALHYAAYFDVPDLVRVLLKGARPRVVNSTCSDFNHGSALHIAASSLCLGAAKCLLEHGANPALRNRKGQVPAEVVPDPMDMSLDKAEAALVAKELRTLLEEAVPLSCALPKVTLPNYDNVPGNLMLSALGLRLGDRVLLDGQKTGTLRFCGTTEFASGQWVGVELDEPEGKNDGSVGGVRYFICPPKQGLFASVSKISKAVDAPPSSVTSTPRTPRMDFSRVTGKGRREHKGKKKTPSSPSLGSLQQRDGAKAEVGDQVLVAGQKQGIVRFYGKTDFAPGYWYGIELDQPTGKHDGSVFGVRYFTCPPRHGVFAPASRIQRIGGSTDSPGDSVGAKKVHQVTMTQPKRTFTTVRTPKDIASENSISRLLFCCWFPWMLRAEMQS
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes.
Palmitoylation by ZDHHC17 regulates association with the plasma membrane.
Cell membrane>Lipid-anchor. Cytoplasm. Golgi apparatus>Golgi stack.
Note: Localized to Golgi stacks as well as on tubulovesicular elements juxtaposed to Golgi cisternae.
Homodimer. Interacts with AKT1 and AKT2; when AKT1 and AKT2 are phosphorylated and activated, affinity is higher for AKT2. Interacts with ZDHHC13 (via ANK repeats). Interacts with ZDHHC17 (via ANK repeats).
Microtubule association is inhibited by the ANK repeats and the Golgi localization region (GoLD).
文献引用
Application: WB Species: rat Sample: spinal cord
Application: IF/ICC Species: rat Sample: astrocytes of the adult spinal cord
Application: IHC Species: rat Sample: spinal cord
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