产品: ABCC3 抗体
货号: DF3874
描述: Rabbit polyclonal antibody to ABCC3
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Rat
预测: Horse
蛋白号: O15438
RRID: AB_2836227

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Rat
克隆:
Polyclonal
特异性:
ABCC3 Antibody detects endogenous levels of total ABCC3.
RRID:
AB_2836227
引用格式: Affinity Biosciences Cat# DF3874, RRID:AB_2836227.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ABC 31; ABC31; ABCC 3; ABCC3; ATP binding cassette sub family C (CFTR/MRP) member 3; ATP binding cassette sub family C member 3; ATP-binding cassette sub-family C member 3; Canalicular multispecific organic anion transporter 2; Canicular multispecific organic anion transporter; CMOAT 2; CMOAT2; EST90757; MLP 2; MLP2; MOAT D; MOAT-D; MOATD; MRP 3; MRP3_HUMAN; Multi specific organic anion transporter D; Multi-specific organic anion transporter D; Multidrug resistance associated protein 3; Multidrug resistance associated protein; Multidrug resistance-associated protein 3; Multispecific organic anion tranporter D;

抗原和靶标

免疫原:

A synthesized peptide derived from human ABCC3, corresponding to a region within the internal amino acids.

基因/基因ID:

研究领域

· Environmental Information Processing > Membrane transport > ABC transporters.

· Human Diseases > Drug resistance: Antineoplastic > Antifolate resistance.

文献引用

1). Curcumol enhances the sensitivity of doxorubicin in triple-negative breast cancer via regulating the miR-181b-2-3p-ABCC3 axis. BIOCHEMICAL PHARMACOLOGY, 2020 (PubMed: 31926937) [IF=5.3]

Application: WB    Species: human    Sample: MDA-MB-231 and MDA-MB-231/ADR cells

Fig. 3.| ABCC3 is a direct target of miR-181b-2-3p.(F) Western blotting analysis of ABCC3 expression in MDA-MB-231 and MDA-MB-231/ADR cells; GAPDH was used as a loading control.

2). Prevention of high-fat/high-sugar diet-induced type 2 diabetes mellitus-associated non-alcoholic fatty liver disease in rats with fermented and raw Rosa roxburghii Tratt (Cili) juice. Frontiers in nutrition, 2025 (PubMed: 40458826) [IF=4.0]

Application: WB    Species: Rat    Sample:

Figure 8. Expression analyses of transcription or protein levels of selected genes. (A) Expression analyses of selected genes by qRT–PCR. The data represent the means ± SDs from six biological replicates with three technical replicates. (B–D) FCJ/RCJ upregulated ABCC3, IDI1, and APOA2 expression in the liver. FCJ and RCJ significantly upregulated hepatic ABCC3 (B) and IDI1 (C) expression, and RCJ significantly upregulated hepatic APOA2 (D) expression in T2DM rats. The data represent the means ± SDs from three biological replicates with three technical replicates. *p < 0.05, ***p < 0.001, ****p < 0.0001.

3). Analysis of ABCC3 in glioma progression: implications for prognosis, immunotherapy, and drug resistance. Discover Oncology, 2025 [IF=2.9]

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