APOL1 Antibody - #DF3785
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3785, RRID:AB_2836142.
展开/折叠
APO L; Apo-L; ApoL; APOL I; ApoL-I; APOL1; APOL1_HUMAN; APOLI; Apolipoprotein L; Apolipoprotein L I; Apolipoprotein L-I; Apolipoprotein L1; FSGS4;
抗原和靶标
Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen.
- O14791 APOL1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTMDPESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQADQEL
翻译修饰 - O14791 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K148 | Ubiquitination | Uniprot | |
T236 | O-Glycosylation | Uniprot | |
N261 | N-Glycosylation | Uniprot | |
T307 | Phosphorylation | Uniprot | |
S311 | Phosphorylation | Uniprot | |
S314 | Phosphorylation | Uniprot |
研究背景
May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.
Phosphorylated by FAM20C in the extracellular medium.
Secreted.
Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen.
In plasma, interacts with APOA1 and mainly associated with large high density lipoprotein particles.
Belongs to the apolipoprotein L family.
研究领域
· Human Diseases > Infectious diseases: Parasitic > African trypanosomiasis.
限制条款
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