| 产品: | APOA4 抗体 |
| 货号: | DF3782 |
| 描述: | Rabbit polyclonal antibody to APOA4 |
| 应用: | WB |
| 反应: | Human |
| 分子量: | 45 KD; 45kD(Calculated). |
| 蛋白号: | P06727 |
| RRID: | AB_2836139 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3782, RRID:AB_2836139.
展开/折叠
Apo AIV; APOA 4; ApoA IV; APOA4; Apolipoprotein A IV; Apolipoprotein A4; MGC142154; MGC142156;
抗原和靶标
- P06727 APOA4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFLKAVVLTLALVAVAGARAEVSADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEVNTYAGDLQKKLVPFATELHERLAKDSEKLKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLRTQVNTQAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKVNSFFSTFKEKESQDKTLSLPELEQQQEQQQEQQQEQVQMLAPLES
研究背景
May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
Phosphorylation sites are present in the extracellular medium.
Secreted.
Synthesized primarily in the intestine and secreted in plasma.
Homodimer.
Nine of the thirteen 22-amino acid tandem repeats (each 22-mer is actually a tandem array of two, A and B, related 11-mers) occurring in this sequence are predicted to be highly alpha-helical, and many of these helices are amphipathic. They may therefore serve as lipid-binding domains with lecithin:cholesterol acyltransferase (LCAT) activating abilities.
Belongs to the apolipoprotein A1/A4/E family.
限制条款
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