AMPH Antibody - #DF3767

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产品: AMPH 抗体
货号: DF3767
描述: Rabbit polyclonal antibody to AMPH
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Rabbit, Dog, Xenopus
分子量: 76 KD; 76kD(Calculated).
蛋白号: P49418
RRID: AB_2836131

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Rabbit(100%), Dog(100%), Xenopus(89%)
克隆:
Polyclonal
特异性:
AMPH Antibody detects endogenous levels of total AMPH.
RRID:
AB_2836131
引用格式: Affinity Biosciences Cat# DF3767, RRID:AB_2836131.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Amp; AMPH 1; AMPH; AMPH_HUMAN; AMPH1; Amphiphysin (Stiff-Man syndrome with breast cancer 128kD autoantigen); Amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen); Amphiphysin; Amphiphysin I; CG8604; Damp; dAmph; Dmel\CG8604; HGNC:471; MGC49429; Stiff man syndrome with breast cancer 128kD autoantigen; Stiff man syndrome with breast cancer 128kDa autoantigen;

抗原和靶标

免疫原:
Uniprot:

P49418(AMPH_HUMAN) >>Visit HPA database.

基因/基因ID:
AMPH(273)
表达:
P49418 AMPH_HUMAN:

Neurons, certain endocrine cell types and spermatocytes.

序列:
MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Dog
100
Rabbit
100
Xenopus
89
Sheep
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P49418 作为底物

Site PTM Type Enzyme
K5 Acetylation
K5 Ubiquitination
T6 Phosphorylation
K11 Acetylation
K15 Acetylation
K23 Acetylation
T34 Phosphorylation
S74 Phosphorylation
K141 Ubiquitination
Y145 Phosphorylation
S147 Phosphorylation
S210 Phosphorylation
S211 Phosphorylation
S250 Phosphorylation
T260 Phosphorylation
S262 Phosphorylation Q13627 (DYRK1A)
S268 Phosphorylation
S272 Phosphorylation Q00535 (CDK5) , P06493 (CDK1) , Q13627 (DYRK1A)
S276 Phosphorylation Q00535 (CDK5) , P06493 (CDK1) , Q13627 (DYRK1A)
S285 Phosphorylation P06493 (CDK1) , Q00535 (CDK5) , Q13627 (DYRK1A)
S293 Phosphorylation Q13627 (DYRK1A) , O76039 (CDKL5) , P28482 (MAPK1) , P27361 (MAPK3)
S295 Phosphorylation P28482 (MAPK1) , Q13627 (DYRK1A) , P27361 (MAPK3)
T310 Phosphorylation Q13627 (DYRK1A)
T312 Phosphorylation Q13627 (DYRK1A)
T350 Phosphorylation P68400 (CSNK2A1)
T387 Phosphorylation P68400 (CSNK2A1)
T445 Phosphorylation
T456 Phosphorylation
S506 Phosphorylation
S549 Phosphorylation
K683 Ubiquitination

研究背景

功能:

May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.

细胞定位:

Cytoplasmic vesicle>Secretory vesicle>Synaptic vesicle membrane>Peripheral membrane protein>Cytoplasmic side. Cytoplasm>Cytoskeleton.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Neurons, certain endocrine cell types and spermatocytes.

亚基结构:

Heterodimer with BIN1 (By similarity). Binds SH3GLB1 (By similarity). Interacts with REPS1 and SGIP1. Binds AP2A2. Interacts with AP2B1. Interacts with DNM1 AND SYNJ1 (By similarity).

研究领域

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

· Organismal Systems > Immune system > Fc gamma R-mediated phagocytosis.   (View pathway)

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