AMPD2 Antibody - #DF3766

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产品: AMPD2 抗体
货号: DF3766
描述: Rabbit polyclonal antibody to AMPD2
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 100 KD; 101kD(Calculated).
蛋白号: Q01433
RRID: AB_2836130

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MS Report
HPLC Report
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说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(91%)
克隆:
Polyclonal
特异性:
AMPD2 Antibody detects endogenous levels of total AMPD2.
RRID:
AB_2836130
引用格式: Affinity Biosciences Cat# DF3766, RRID:AB_2836130.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Adenosine monophosphate deaminase 2 (isoform L); Adenosine monophosphate deaminase 2; adenosine monophosphate deaminase 2 isoform L; AMP deaminase 2; AMP deaminase isoform L; AMPD 2; AMPD; AMPD2; AMPD2_HUMAN; RP5-1160K1.5; SPG63;

抗原和靶标

免疫原:
Uniprot:

Q01433(AMPD2_HUMAN) >>Visit HPA database.

基因/基因ID:
AMPD2(271)
表达:
Q01433 AMPD2_HUMAN:

Highly expressed in cerebellum.

序列:
MRNRGQGLFRLRSRCFLHQSLPLGAGRRKGLDVAEPGPSRCRSDSPAVAAVVPAMASYPSGSGKPKAKYPFKKRASLQASTAAPEARGGLGAPPLQSARSLPGPAPCLKHFPLDLRTSMDGKCKEIAEELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHPPALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRVGYRYETLCQELALITQAVQSEMLETIPEEAGITMSPGPQ

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
91
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q01433 作为底物

Site PTM Type Enzyme
R2 Methylation
R4 Methylation
Q6 Methylation
S13 Phosphorylation
S43 Phosphorylation
S45 Phosphorylation
S60 Phosphorylation
S76 Phosphorylation
R87 Methylation
S97 Phosphorylation
R99 Methylation
S100 Phosphorylation
K109 Ubiquitination
T117 Phosphorylation
S118 Phosphorylation
K124 Ubiquitination
S134 Phosphorylation
S138 Phosphorylation
S142 Phosphorylation
Y145 Phosphorylation
S151 Phosphorylation
S168 Phosphorylation
K182 Ubiquitination
K187 Ubiquitination
T188 Phosphorylation
S190 Phosphorylation
S192 Phosphorylation
Y197 Phosphorylation
K198 Ubiquitination
S208 Phosphorylation
K229 Ubiquitination
C230 S-Nitrosylation
K242 Ubiquitination
Y254 Phosphorylation
K276 Ubiquitination
T289 Phosphorylation
S292 Phosphorylation
Y307 Phosphorylation
T314 Phosphorylation
K372 Sumoylation
K414 Ubiquitination
K489 Ubiquitination
K493 Ubiquitination
Y494 Phosphorylation
S500 Phosphorylation
K508 Ubiquitination
T509 Phosphorylation
K516 Acetylation
S527 Phosphorylation
K533 Ubiquitination
Y721 Phosphorylation
K812 Ubiquitination
R839 Methylation
S875 Phosphorylation

研究背景

功能:

AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle.

翻译修饰:

Methylated at Gln-6 by N6AMT1.

组织特异性:

Highly expressed in cerebellum.

亚基结构:

Homotetramer.

蛋白家族:

Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

研究领域

· Metabolism > Nucleotide metabolism > Purine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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