产品: EXO1 抗体
货号: DF3615
描述: Rabbit polyclonal antibody to EXO1
应用: WB IHC IF/ICC
文献验证: IHC
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog
蛋白号: Q9UQ84
RRID: AB_2835987

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 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
EXO1 Antibody detects endogenous levels of total EXO1.
RRID:
AB_2835987
引用格式: Affinity Biosciences Cat# DF3615, RRID:AB_2835987.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

exo1; EXO1_HUMAN; ExoI; Exonuclease 1; Exonuclease I; Exonuclease1; HEX1; hExo I; hExo1; hExoI; Rad2 nuclease family member homolog of S. cerevisiae exonuclease 1;

抗原和靶标

免疫原:

A synthesized peptide derived from human EXO1, corresponding to a region within N-terminal amino acids.

基因/基因ID:

研究领域

· Genetic Information Processing > Replication and repair > Mismatch repair.

文献引用

1). Exonuclease 1 (EXO1) is a Potential Prognostic Biomarker and Correlates with Immune Infiltrates in Lung Adenocarcinoma. OncoTargets and therapy, 2021 (PubMed: 33623391) [IF=2.7]

Application: IHC    Species: human    Sample:

Figure 3 Expression and prognostic value of EXO1 in our cohort. (A) HE staining of EXO1 in tumor and matched normal tissue samples, Scale Bar for × 40 images, 50 μm. Positive staining (brown) of EXO1 was detected in tumoral epithelial cells, macrophages, and partially positive in vascular endothelial cells in tumor tissues. And positive staining of EXO1 in macrophages and partially positive in normal epithelial cells and vascular endothelial cells in normal tissues. EXO1 was negative in stromal cells in both tumor and normal tissues. (B) Immunohistochemistry scores showed that EXO1 was highly expressed in LUAD tumor tissue samples compared with normal tissue samples. (C) Kaplan-Meier survival analysis indicated that a high EXO1 immunohistochemistry score was associated with poor OS in LUAD patients. **p

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