IL17RA Antibody - #DF3602

Figure 4. Effect of GA on regulating IL‐17RA signaling and downstream signaling in DSS‐induced colitis mice. A) KEGG analysis. B) Heatmap of IL‐17RA signaling and downstream signaling genes. C) The fold change (fc), p value and false discovery rate (FDR) of IL‐17 signaling key genes. D) Circos represents different genes and different groups, the innermost lines showed the connections between the genes and groups. The thickness of the lines indicates the expressions levels of genes. E–G) Western blot analysis for IL‐17 signaling and downstream signaling proteins in colonic tissues of colitis mice. All data are expressed as mean ± S.E.M (n = 3). *P < 0.05 and **P < 0.01 compared with the control group, #P < 0.05 and ## P < 0.01 compared with the DSS group.

FIGURE 10 | Protein expression of seven model genes. (A–C) Immunohistochemical staining images of MMP14 (A), PCDH7 (B), and LAMP3 (C) from the HPA database. (D) Western blotting results shows the protein expression of BTG2, TLR2, CCL20, and IL7R in a normal bronchial epithelial cell line (16-HBS) and lung adenocarcinoma cell line (A549).

Fig. 2 FOSL1 was upregulated in wound tissues. (A) Macroscopy view of wound healing on days 0, 1, 2, 3, 7, 14 mice. Scale bar: 1 mm. (B) A mouse back full-thickness skin resection trauma model in days 0, 1, 2, 3,7, The FOSL1 mRNA expression was determined by qPCR in 14. (C) A mouse back full-thickness skin resection trauma model in days 0, 1, 2, 3, 7, 14 FOSL1 protein expression was determined by Western Blot. (D) Quantification of C. All bars represent mean ± SD (n = 6). (E) qPCR detection of IL17A and IL17RA mRNA expression in traumatic epidermal tissue. (F, G) Western Blot test for the expression of IL17A and IL17RA proteins in traumatic epidermal tissue; Quantification of F. All bars represent mean ± SD (n = 3). *, P 

Fig. 2 Immunohistochemical staining and scoring of prostate cancer tissue and para-carcinoma tissue after NHT(×400). A IL-17 A in prostate cancer tissue(×400) B. IL-17 A in para-carcinoma tissue(×400) C. IL-17RA in prostate cancer tissue (×400) D. IL-17RA in para-carcinoma tissue(×400) E. IL-17RC in prostate cancer tissue(×400) F. IL-17RC in para-carcinoma tissue(×400) G. IL-17 A in PCa was significantly higher than that in NP (P 

Fig. 4: Effect of GA on regulating IL-17 signal and downstream signals in DSS - induced colitis mice. (A) KEGG analysis. (B) Heatmap of IL-17 signal and downstream signals genes. (C) The fold change (fc), p value and false discovery rate (FDR) of IL-17 signal key genes. (D), (E) and (F) Western blot analysis for IL-17 This preprint research paper has not been peer reviewed. Electronic copy available at: https://ssrn.com/abstract=4526520 Preprint not peer reviewed signal and downstream signals proteins in colonic tissues of colitis mice. (G) Mantel test analysis. (H) Corr_heatmap analysis. All data are expressed as mean ± S.E.M (n=3). *P < 0.05 and **P < 0.01 compared with the control group, #P < 0.05 and ##P < 0.01 compared with the DSS group.