Cytochrome P450 26C1 Antibody - #DF3570

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产品: Cytochrome P450 26C1 抗体
货号: DF3570
描述: Rabbit polyclonal antibody to Cytochrome P450 26C1
应用: WB IHC
反应: Human, Mouse
预测: Pig, Bovine, Sheep, Rabbit
分子量: 0 KD; 57kD(Calculated).
蛋白号: Q6V0L0
RRID: AB_2835942

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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(82%), Bovine(91%), Sheep(91%), Rabbit(100%)
克隆:
Polyclonal
特异性:
Cytochrome P450 26C1 Antibody detects endogenous levels of total Cytochrome P450 26C1.
RRID:
AB_2835942
引用格式: Affinity Biosciences Cat# DF3570, RRID:AB_2835942.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CP26C_HUMAN; cyp26b1l; CYP26C1; cyp26d1; Cytochrome P450 26C1; Cytochrome P450 family 26 subfamily C polypeptide 1; Cytochrome P450, subfamily XXVIC polypeptide 1; EG546726; FFDD4; FLJ45301; MGC158120; retinoic acid catabolizing enzyme;

抗原和靶标

免疫原:
Uniprot:

Q6V0L0(CP26C_HUMAN) >>Visit HPA database.

基因/基因ID:
CYP26C1(340665)
表达:
Q6V0L0 CP26C_HUMAN:

Detected in most tissues at very low level.

序列:
MFPWGLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCAAGGPVSVYDASKALTFRMAARILLGLRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLRKGIRARDQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELKESAVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPAMQTVPIVHPVDGLRLFFHPLTPSVAGNGLCL

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Rabbit
100
Bovine
91
Sheep
91
Pig
82
Xenopus
67
Chicken
60
Zebrafish
58
Horse
0
Dog
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q6V0L0 作为底物

Site PTM Type Enzyme
Y80 Phosphorylation
S150 Phosphorylation
T300 Phosphorylation
K321 Ubiquitination

研究背景

功能:

Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).

细胞定位:

Membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Detected in most tissues at very low level.

蛋白家族:

Belongs to the cytochrome P450 family.

研究领域

· Metabolism > Metabolism of cofactors and vitamins > Retinol metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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