CDCA2 Antibody - #DF3543

Figure 1 Expression of CDCA2 in hepatocellular carcinoma. Analysis of an RNA-seq dataset from UALCAN showed (A) elevated CDCA2 expression in primary HCC tissues compared with normal liver tissues; (B) increased CDCA2 levels with clinical stage; (C) elevated CDCA2 expression in samples expressing mutant TP53 compared with samples expressing wild-type TP53; (D) worse survival of patients with high CDCA2 expression than in patients with low CDCA2 expression; and (E) worse survival of patients with high CDCA2 expression than patients with low CDCA2 expression among Asian patients but not among White Caucasian patients. (F) Our study found elevated CDCA2 mRNA levels in 40 HCC tissues compared to paired normal liver tissues. (G) Representative photos of +ve and –ve immunohistochemistry staining of CDCA2 in HCC or normal liver tissues. (H) qRT-PCR measured CDCA2 mRNA expression in the L02 and HCC cell lines. (I) Western blotting analysis of CDCA2 protein expression in the L02 and HCC cell lines. Stars indicate the P value of the CDCA2 protein level compared with that in the L02 cells. (J) Western blotting analysis of CDCA2 protein expression in HCC cell lines with lentivirus-mediated stable CDCA2 knockdown. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001.