| 产品: | RPS23 抗体 |
| 货号: | DF3682 |
| 描述: | Rabbit polyclonal antibody to RPS23 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 16 KD; 16kD(Calculated). |
| 蛋白号: | P62266 |
| RRID: | AB_2835892 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3682, RRID:AB_2835892.
展开/折叠
40S ribosomal protein S23; FLJ35016; Homolog of yeast ribosomal protein S28; Ribosomal protein S23; RPS 23; RPS23; RS23_HUMAN; S23;
抗原和靶标
- P62266 RS23_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P62266 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K25 | Ubiquitination | Uniprot | |
| K29 | Sumoylation | Uniprot | |
| K29 | Ubiquitination | Uniprot | |
| K37 | Sumoylation | Uniprot | |
| K37 | Ubiquitination | Uniprot | |
| K48 | Sumoylation | Uniprot | |
| K48 | Ubiquitination | Uniprot | |
| K54 | Sumoylation | Uniprot | |
| K54 | Ubiquitination | Uniprot | |
| K60 | Ubiquitination | Uniprot | |
| K76 | Ubiquitination | Uniprot | |
| K80 | Ubiquitination | Uniprot | |
| K108 | Ubiquitination | Uniprot | |
| S129 | Phosphorylation | Uniprot | |
| Y134 | Phosphorylation | Uniprot | |
| K135 | Acetylation | Uniprot |
研究背景
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays an important role in translational accuracy.
Hydroxylation at Pro-62 affects translation termination efficiency.
Cytoplasm>Cytosol. Cytoplasm. Rough endoplasmic reticulum.
Note: Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Component of the 40S small ribosomal subunit.
Belongs to the universal ribosomal protein uS12 family.
研究领域
· Genetic Information Processing > Translation > Ribosome.
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