MOS Antibody - #AF0355

(2)  
产品: MOS 抗体
货号: AF0355
描述: Rabbit polyclonal antibody to MOS
应用: WB IF/ICC
反应: Human, Monkey
预测: Pig, Zebrafish, Bovine, Dog, Chicken, Xenopus
分子量: 40kDa; 38kD(Calculated).
蛋白号: P00540
RRID: AB_2833521

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 200ul RMB¥ 3000 现货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Monkey
预测:
Pig(91%), Zebrafish(88%), Bovine(82%), Dog(91%), Chicken(91%), Xenopus(82%)
克隆:
Polyclonal
特异性:
MOS Antibody detects endogenous levels of total MOS.
RRID:
AB_2833521
引用格式: Affinity Biosciences Cat# AF0355, RRID:AB_2833521.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

c mos; MGC119962; MGC119963; MOS; MOS_HUMAN; MSV; Oocyte maturation factor mos; Proto oncogene serine / threonine protein kinase mos; Proto-oncogene c-Mos; Proto-oncogene serine/threonine-protein kinase mos; v mos Moloney murine sarcoma viral oncogene homolog;

抗原和靶标

免疫原:
Uniprot:

P00540(MOS_HUMAN) >>Visit HPA database.

基因/基因ID:
MOS(4342)
表达:
P00540 MOS_HUMAN:

Expressed specifically in testis during spermatogenesis.

描述:
Mos a proto-oncogenic serine/threonine kinase of the MOS family. Expressed predominantly in germ cells. Crucial for normal oocyte meiosis and female fertility in mice.
序列:
MPSPLALRPYLRSEFSPSVDARPCSSPSELPAKLLLGATLPRAPRLPRRLAWCSIDWEQVCLLQRLGAGGFGSVYKATYRGVPVAIKQVNKCTKNRLASRRSFWAELNVARLRHDNIVRVVAASTRTPAGSNSLGTIIMEFGGNVTLHQVIYGAAGHPEGDAGEPHCRTGGQLSLGKCLKYSLDVVNGLLFLHSQSIVHLDLKPANILISEQDVCKISDFGCSEKLEDLLCFQTPSYPLGGTYTHRAPELLKGEGVTPKADIYSFAITLWQMTTKQAPYSGERQHILYAVVAYDLRPSLSAAVFEDSLPGQRLGDVIQRCWRPSAAQRPSARLLLVDLTSLKAELG

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
91
Dog
91
Chicken
91
Zebrafish
88
Bovine
82
Xenopus
82
Horse
0
Sheep
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P00540 作为底物

Site PTM Type Enzyme
S3 Phosphorylation
S16 Phosphorylation
Y263 Phosphorylation
T339 Phosphorylation
S340 Phosphorylation

翻译修饰 - P00540 作为激酶

Substrate Site Source
P08670 (VIM) T458 Uniprot
P08670 (VIM) S459 Uniprot
Q02750 (MAP2K1) S218 Uniprot
Q02750 (MAP2K1) S222 Uniprot

研究背景

组织特异性:

Expressed specifically in testis during spermatogenesis.

蛋白家族:

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

研究领域

· Cellular Processes > Cell growth and death > Oocyte meiosis.   (View pathway)

· Cellular Processes > Cell motility > Regulation of actin cytoskeleton.   (View pathway)

· Organismal Systems > Endocrine system > Progesterone-mediated oocyte maturation.

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