UTP14A Antibody - #DF3418

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产品: UTP14A 抗体
货号: DF3418
描述: Rabbit polyclonal antibody to UTP14A
应用: WB IF/ICC
反应: Human, Mouse
预测: Pig, Horse, Dog
分子量: 85 KD; 88kD(Calculated).
蛋白号: Q9BVJ6
RRID: AB_2835800

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(88%), Horse(88%), Dog(88%)
克隆:
Polyclonal
特异性:
UTP14A Antibody detects endogenous levels of total UTP14A.
RRID:
AB_2835800
引用格式: Affinity Biosciences Cat# DF3418, RRID:AB_2835800.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Antigen NY CO 16; KIAA0266; SDCCAG16; Serologically defined colon cancer antigen 16; U3 small nucleolar RNA associated protein 14 homolog A; UTP14;

抗原和靶标

免疫原:
Uniprot:

Q9BVJ6(UT14A_HUMAN) >>Visit HPA database.

基因/基因ID:
UTP14A(10813)
表达:
Q9BVJ6 UT14A_HUMAN:

Ubiquitously expressed.

序列:
MTANRLAESLLALSQQEELADLPKDYLLSESEDEGDNDGERKHQKLLEAISSLDGKNRRKLAERSEASLKVSEFNVSSEGSGEKLVLADLLEPVKTSSSLATVKKQLSRVKSKKTVELPLNKEEIERIHREVAFNKTAQVLSKWDPVVLKNRQAEQLVFPLEKEEPAIAPIEHVLSGWKARTPLEQEIFNLLHKNKQPVTDPLLTPVEKASLRAMSLEEAKMRRAELQRARALQSYYEAKARREKKIKSKKYHKVVKKGKAKKALKEFEQLRKVNPAAALEELEKIEKARMMERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLSKNKELTQKLQVASESEEEEGGTEDVEELLVPDVVNEVQMNADGPNPWMLRSCTSDTKEAATQEDPEQLPELEAHGVSESEGEERPVAEEEILLREFEERRSLRKRSELSQDAEPAGSQETKDSGSQEVLSELRVLSQKLKENHQSRKQKASSEGTIPQVQREEPAPEEEEPLLLQRPERVQTLEELEELGKEECFQNKELPRPVLEGQQSERTPNNRPDAPKEKKKKEQMIDLQNLLTTQSPSVKSLAVPTIEELEDEEERNHRQMIKEAFAGDDVIRDFLKEKREAVEASKPKDVDLTLPGWGEWGGVGLKPSAKKRRRFLIKAPEGPPRKDKNLPNVIINEKRNIHAAAHQVRVLPYPFTHHWQFERTIQTPIGSTWNTQRAFQKLTTPKVVTKPGHIINPIKAEDVGYRSSSRSDLSVIQRNPKRITTRHKKQLKKCSVD

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
88
Horse
88
Dog
88
Bovine
75
Rabbit
75
Chicken
67
Sheep
0
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9BVJ6 作为底物

Site PTM Type Enzyme
S9 Phosphorylation
S14 Phosphorylation
Y26 Phosphorylation
S29 Phosphorylation
S31 Phosphorylation
K45 Sumoylation
S52 Phosphorylation
K56 Acetylation
S65 Phosphorylation
S77 Phosphorylation
S78 Phosphorylation
S81 Phosphorylation
S99 Phosphorylation
T102 Phosphorylation
K136 Methylation
K143 Ubiquitination
K179 Ubiquitination
K194 Ubiquitination
K196 Ubiquitination
T205 Phosphorylation
K288 Ubiquitination
K298 Methylation
K307 Methylation
K309 Methylation
K314 Sumoylation
S341 Phosphorylation
S343 Phosphorylation
T389 Phosphorylation
S405 Phosphorylation
S407 Phosphorylation
S429 Phosphorylation
S434 Phosphorylation
S437 Phosphorylation
S445 Phosphorylation
T448 Phosphorylation
S451 Phosphorylation
S453 Phosphorylation
S458 Phosphorylation
S479 Phosphorylation
S480 Phosphorylation
T510 Phosphorylation
S538 Phosphorylation
T541 Phosphorylation
S569 Phosphorylation
S571 Phosphorylation
K620 Sumoylation
K640 Ubiquitination
S642 Phosphorylation
K652 Methylation
K662 Ubiquitination
K672 Ubiquitination
T701 Phosphorylation
K733 Acetylation
K733 Sumoylation
S741 Phosphorylation
S743 Phosphorylation
S748 Phosphorylation

研究背景

功能:

May be required for ribosome biogenesis.

翻译修饰:

Citrullinated by PADI4.

细胞定位:

Nucleus>Nucleolus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitously expressed.

蛋白家族:

Belongs to the UTP14 family.

研究领域

· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.

文献引用

1). Overexpression of U three protein 14a (UTP14a) is associated with poor prognosis of esophageal squamous cell carcinoma. Thoracic Cancer (PubMed: 31496055) [IF=2.9]

Application: IHC    Species: human    Sample: esophageal squamous cell carcinoma (ESCC) and CDM tissues

Figure 1 |IHC staining and Western blot analysis of UTP14a in esophageal squamous cell carcinoma (ESCC) and CDM tissues. (a–d) Negative to strong UTP14a expression in ESCC tissues.

Application: WB    Species: human    Sample: ESCC and CDM tissue

Figure 1 |IHC staining and Western blot analysis of UTP14a in esophageal squamous cell carcinoma (ESCC) and CDM tissues. (a–d) Negative to strong UTP14a expression in ESCC tissues.(e–f) Negative-to-moderate UTP14a expression in CDM tissues. (h) Western blot analysis of six pairs of ESCC and CDM tissue.

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