PARD3 Antibody - #DF3368

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产品: PARD3 抗体
货号: DF3368
描述: Rabbit polyclonal antibody to PARD3
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Bovine, Horse, Sheep, Rabbit, Dog, Chicken
蛋白号: Q8TEW0
RRID: AB_2835750

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
PARD3 Antibody detects endogenous levels of total PARD3.
RRID:
AB_2835750
引用格式: Affinity Biosciences Cat# DF3368, RRID:AB_2835750.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

agouti signaling protein; ASIP; Atypical PKC isotype specific interacting protein; Atypical PKC isotype-specific-interacting protein; Baz; bazooka; Coagulation factor II receptor-like 2; CTCL tumor antigen se2-5; F2rl2; PAR-3; par-3 family cell polarity regulator alpha; par-3 family cell polarity regulator; PAR3 alpha; par3; PAR3-alpha; PARD-3; Pard3; PARD3_HUMAN; PARD3A; Partitioning defective 3 homolog; Partitioning-defective 3 homolog; Partitioning-defective protein 3, C. elegans, homolog of; SE2-5L16; SE2-5LT1; SE2-5T2; Thrombin receptor-like 2;

抗原和靶标

免疫原:

A synthesized peptide derived from human PARD3, corresponding to a region within C-terminal amino acids.

基因/基因ID:
PARD3(56288)

研究领域

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

· Cellular Processes > Cellular community - eukaryotes > Adherens junction.   (View pathway)

· Cellular Processes > Cellular community - eukaryotes > Tight junction.   (View pathway)

· Environmental Information Processing > Signal transduction > Rap1 signaling pathway.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

· Environmental Information Processing > Signal transduction > Hippo signaling pathway.   (View pathway)

· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.

· Organismal Systems > Immune system > Chemokine signaling pathway.   (View pathway)

· Organismal Systems > Development > Axon guidance.   (View pathway)

文献引用

1). Discovery of the Natural Bibenzyl Compound Erianin in Dendrobium Inhibiting the Growth and EMT of Gastric Cancer through Downregulating the LKB1-SIK2/3-PARD3 Pathway. International journal of molecular sciences, 2024 (PubMed: 39063214) [IF=5.6]
2). Constitutive activation of β-catenin in odontoblasts induces aberrant pulp calcification in mouse incisors. JOURNAL OF MOLECULAR HISTOLOGY, 2021 (PubMed: 33689044) [IF=2.9]

Application: WB    Species: Mouse    Sample: calcification tissue

Fig. 6 Downregulation of polarity-related downstream molecules in incisor odontoblasts on day 13.5. a RT-qPCR quantification analy- sis of intercellular junction-related genes and polarity-related down- stream genes. CA-β-catenin mice displayed downregulated expres- sion levels of N-cadherin, ZO-1, Cdc42, Par3, Par6 and aPKC. b Western blot analysis of intercellular junction-related proteins and polarity-related downstream proteins. The fold activation data analy- sis is shown in (c). CA-β-catenin mice exhibited lower expression levels of N-cadherin, ZO-1, Cdc42, Par3, Par6 and aPKC. *p < 0.05, **p < 0.01, ***p < 0.001, n = 6. (Color figure online)

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