产品: CTLA4 重组兔单抗
货号: BF4618
描述: Rabbit monoclonal antibody to CTLA4
应用: WB IHC
反应: Human, Mouse
蛋白ID: P16410

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   规格 价格 库存
 50ul RMB¥ 1100 1250 现货
 100ul RMB¥ 2100 2300 现货

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产品描述

来源:
Rabbit IgG
应用:
WB 1:1000, IHC 1:200-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Monoclonal [ReFirm24068]
特异性:
CTLA4 Recombinant Rabbit mAb detects endogenous levels of CTLA4.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ALPS5; CD 152; CD; CD152; CD152 antigen; CD152 isoform; Celiac disease 3; CELIAC3; CTLA 4; CTLA-4; CTLA4; CTLA4_HUMAN; Cytotoxic T cell associated 4; Cytotoxic T lymphocyte antigen 4; Cytotoxic T lymphocyte associated 4; Cytotoxic T lymphocyte associated 4, soluble isoform, included; Cytotoxic T lymphocyte associated antigen 4; Cytotoxic T lymphocyte associated antigen 4 short spliced form; Cytotoxic T lymphocyte associated protein 4; Cytotoxic T lymphocyte associated serine esterase 4; Cytotoxic T lymphocyte protein 4; Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; GRD4; GSE; ICOS; IDDM12; insulin-dependent diabetes mellitus 12; Ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; OTTHUMP00000216623;

抗原和靶标

免疫原:

A synthetic peptide from human CTLA4

基因/基因ID:
描述:
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain,a transmembrane domain,and a cytoplasmic tail. Alternate transcriptional splice variants,encoding different isoforms,have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond,while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus,Graves disease,Hashimoto thyroiditis,celiac disease,systemic lupus erythematosus,thyroid-associated orbitopathy,and other autoimmune diseases.

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs).   (View pathway)

· Human Diseases > Immune diseases > Autoimmune thyroid disease.

· Human Diseases > Immune diseases > Rheumatoid arthritis.

· Organismal Systems > Immune system > T cell receptor signaling pathway.   (View pathway)

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