ALKBH5 Recombinant Rabbit mAb - #BF4365

ReFirm 重组兔单抗
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产品: ALKBH5 重组兔单抗
货号: BF4365
描述: Rabbit monoclonal antibody to ALKBH5
应用: WB IHC
反应: Human, Mouse, Rat
蛋白ID: Q6P6C2

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   规格 价格 库存
 50ul RMB¥ 1100 1250 现货
 100ul RMB¥ 2100 2300 现货

货期: 当天发货

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit IgG
应用:
WB 1:1000, IHC 1:200-1:2000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Monoclonal [ReFirm23815]
特异性:
ALKBH5 Recombinant Rabbit mAb detects endogenous levels of ALKBH5.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ABH5; AlkB, alkylation repair homolog 5 (E. coli); AlkB, alkylation repair homolog 5; Alkylated DNA repair protein alkB homolog 5; Alpha ketoglutarate dependent dioxygenase alkB homolog 5; OFOXD; OFOXD1; Oxoglutarate and iron-dependent oxygenase domain containing; Probable alpha ketoglutarate dependent dioxygenase ABH5; RNA demethylase ALKBH5;

抗原和靶标

免疫原:

A synthetic peptide from human ALKBH5

基因/基因ID:
ALKBH5(54890)
描述:
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N6-methyladenosine (m6A) RNA,the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736,PubMed:24778178,PubMed:24616105,PubMed:24489119). Can also demethylate N6-methyladenosine in single-stranded DNA (in vitro) (PubMed:24616105). Requires molecular oxygen,alpha-ketoglutarate and iron (PubMed:21264265,PubMed:23177736,PubMed:24778178,PubMed:24616105,PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).

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