Factor D/CFD Recombinant Rabbit mAb - #BF4292

WB 1:1000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

Human

Monoclonal [ReFirm23742]

Factor D/CFD Recombinant Rabbit mAb detects endogenous levels of Factor D/CFD.

Unconjugated.

Affinity-chromatography.

Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

This gene encodes a member of the S1,or chymotrypsin,family of serine peptidases. This protease catalyzes the cleavage of factor B,the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine,a cell signaling protein secreted by adipocytes,which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency,which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.