TRAF4 Recombinant Rabbit mAb - #BF4212

WB 1:1000-1:3000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

Human, Mouse

Monoclonal [ReFirm23659]

TRAF4 Recombinant Rabbit mAb detects endogenous levels of TRAF4.

Unconjugated.

Affinity-chromatography.

Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with,and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor,p75 (NTR,NTSR1),and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox,a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus,is thought to be involved in the oxidative activation of MAPK8,JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.