Caveolin 3 Recombinant Rabbit mAb - #BF4113

WB 1:1000-1:3000, IHC 1:200-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

Human, Mouse, Rat

Monoclonal [ReFirm23560]

Caveolin 3 Recombinant Rabbit mAb detects endogenous levels of Caveolin 3.

Unconjugated.

Affinity-chromatography.

Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

This gene encodes a caveolin family member,which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing,disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C),hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus,with inclusion or exclusion of a differentially spliced intron. In addition,transcripts utilize multiple polyA sites and contain two potential translation initiation sites.