产品描述

来源:
Rabbit IgG
应用:
WB 1:1000, IHC 1:200-1:500, ICC
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Monoclonal [ReFirm23470]
特异性:
Brm Recombinant Rabbit mAb detects endogenous levels of Brm.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ATP dependent helicase SMARCA2; ATP-dependent helicase SMARCA2; BAF190; BAF190B; BRG1-associated factor 190B; BRM; FLJ36757; Global transcription activator homologous sequence; hBRM; hSNF2a; MGC74511; Possible global transcription activator SNF2L2; Probable global transcription activator SNF2L2; Protein brahma homolog; SMARCA2; SMCA2_HUMAN; SNF2 alpha; SNF2 like 2; SNF2-alpha; SNF2/SWI2 like protein 2; SNF2L2; SNF2LA; Sth1p; Sucrose nonfermenting 2 like protein 2; SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2;

抗原和靶标

免疫原:

A synthetic peptide from human Brm

基因/基因ID:
描述:
The protein encoded by this gene is a member of the SWI,SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF,SWI,which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene,which contains a trinucleotide repeat (CAG) length polymorphism.

研究领域

· Human Diseases > Cancers: Specific types > Hepatocellular carcinoma.   (View pathway)

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