| 产品: | BAP31 抗体 |
| 货号: | DF3198 |
| 描述: | Rabbit polyclonal antibody to BAP31 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Dog, Chicken |
| 分子量: | 28 KD; 28kD(Calculated). |
| 蛋白号: | P51572 |
| RRID: | AB_2835578 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3198, RRID:AB_2835578.
展开/折叠
6C6 AG; 6C6 AG tumor associated antigen; 6C6-AG tumor-associated antigen; 6C6AG; 6C6AG tumor associated antigen; Accessory protein BAP 31; Accessory protein BAP31; B cell receptor associated protein 31; B-cell receptor-associated protein 31; BA31; BAP 31; Bap31; BAP31_HUMAN; BCAP 31; BCAP31; BCR associated protein Bap 31; BCR associated protein Bap31; BCR-associated protein 31; CDM; CDM protein; DXS1357E; MS950; p28; p28 Bap31; Protein CDM; RP23-329M9.5;
抗原和靶标
- P51572 BAP31_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILVLLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P51572 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y73 | Phosphorylation | Uniprot | |
| K79 | Ubiquitination | Uniprot | |
| K95 | Acetylation | Uniprot | |
| K95 | Ubiquitination | Uniprot | |
| K138 | Ubiquitination | Uniprot | |
| K149 | Ubiquitination | Uniprot | |
| K158 | Ubiquitination | Uniprot | |
| K159 | Ubiquitination | Uniprot | |
| K167 | Ubiquitination | Uniprot | |
| K176 | Acetylation | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| K185 | Ubiquitination | Uniprot | |
| K190 | Acetylation | Uniprot | |
| K190 | Ubiquitination | Uniprot | |
| K192 | Ubiquitination | Uniprot | |
| S197 | Phosphorylation | Uniprot | |
| K199 | Ubiquitination | Uniprot | |
| K204 | Acetylation | Uniprot | |
| K204 | Ubiquitination | Uniprot | |
| K214 | Ubiquitination | Uniprot | |
| S216 | Phosphorylation | Uniprot | |
| K221 | Ubiquitination | Uniprot | |
| K232 | Ubiquitination | Uniprot | |
| K243 | Ubiquitination | Uniprot | |
| K244 | Ubiquitination | Uniprot |
研究背景
Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8-mediated apoptosis.
Cleaved by CASP8 and other caspases.
Endoplasmic reticulum membrane>Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane>Multi-pass membrane protein.
Note: May shuttle between the ER and the intermediate compartment/cis-Golgi complex.
Ubiquitous. Highly expressed in neurons and discrete endocrine cells.
Homodimer and heterodimer with BCAP29. Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II. Interacts with HACD2.
(Microbial infection) Interacts (via C-terminus) with HRSV membrane protein SH; this interaction is direct.
Belongs to the BCAP29/BCAP31 family.
研究领域
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.
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