IFIH1 Recombinant Rabbit mAb - #BF3798

WB 1:1000-1:3000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

Human, Mouse, Rat

Monoclonal [ReFirm23245]

IFIH1 Recombinant Rabbit mAb detects endogenous levels of IFIH1.

Unconjugated.

Affinity-chromatography.

Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

DEAD box proteins,characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD),are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation,nuclear and mitochondrial splicing,and ribosome and spliceosome assembly. Based on their distribution patterns,some members of this family are believed to be involved in embryogenesis,spermatogenesis,and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound,mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents,treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.