Recoverin Antibody - #DF3160

Figure 2. Histological characterization of recoverin-induced EAU in rabbits. Morphology of the posterior sector of the eye before (A,B) and 4 weeks after (C,D) immunization with recombinant bovine recoverin (7.5 mg/mL in PBS) mixed with Freund’s complete adjuvant (1:1). Inflammatory mononuclear cells infiltrating the vitreous body and retina (D, short black arrows), Dalen–Fuchs nodules (C,D, white arrows), the swelling of photoreceptors up to their fusion into homogeneous eosinophilic droplets (D, red arrows), activation of the Müller glia (D, red arrowheads) and areas of retinal atrophy (C,D, long black arrows) are indicated. Retinal thickness in images (C,D) is altered relative to images (A,B) due to inflammatory and atrophic changes. Retinal fissures and detachment are of artificial origin. Staining by hematoxylin and eosin. Magnification: 200× (top row) or 400× (bottom row). Scale bar 100 µm on (A) (top row) and 50 µm on (B) (bottom row).