CSTF2 Antibody - #DF3158

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产品: CSTF2 抗体
货号: DF3158
描述: Rabbit polyclonal antibody to CSTF2
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 60 KD; 61kD(Calculated).
蛋白号: P33240
RRID: AB_2835535

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
克隆:
Polyclonal
特异性:
CSTF2 Antibody detects endogenous levels of total CSTF2.
RRID:
AB_2835535
引用格式: Affinity Biosciences Cat# DF3158, RRID:AB_2835535.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

betaCstF 64 variant 2; CF-1 64 kDa subunit; CF1 64 kDa subunit; Cleavage stimulation factor 64 kDa subunit; Cleavage stimulation factor subunit 2; Cleavage stimulation factor, 3' pre RNA, subunit 2, 64kDa; CSTF 2; CstF 64; CSTF 64 kDa subunit; CstF-64; CSTF2; CSTF2_HUMAN; MGC188397;

抗原和靶标

免疫原:
Uniprot:

P33240(CSTF2_HUMAN) >>Visit HPA database.

基因/基因ID:
CSTF2(1478)
序列:
MAGLTVRDPAVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGTGAPVIESPYGETISPEDAPESISKAVASLPPEQMFELMKQMKLCVQNSPQEARNMLLQNPQLAYALLQAQVVMRIVDPEIALKILHRQTNIPTLIAGNPQPVHGAGPGSGSNVSMNQQNPQAPQAQSLGGMHVNGAPPLMQASMQGGVPAPGQMPAAVTGPGPGSLAPGGGMQAQVGMPGSGPVSMERGQVPMQDPRAAMQRGSLPANVPTPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHVPGHESRGPPPHELRGGPLPEPRPLMAEPRGPMLDQRGPPLDGRGGRDPRGIDARGMEARAMEARGLDARGLEARAMEARAMEARAMEARAMEARAMEVRGMEARGMDTRGPVPGPRGPIPSGMQGPSPINMGAVVPQGSRQVPVMQGTGMQGASIQGGSQPGGFSPGQNQVTPQDHEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAP

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Zebrafish
100
Chicken
100
Rabbit
100
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P33240 作为底物

Site PTM Type Enzyme
S14 Phosphorylation
K96 Ubiquitination
S113 Phosphorylation
Y115 Phosphorylation
T118 Phosphorylation
S120 Phosphorylation
K130 Ubiquitination
K145 Ubiquitination
K148 Ubiquitination
S154 Phosphorylation
K189 Ubiquitination
R303 Methylation
R308 Methylation
S310 Phosphorylation
T317 Phosphorylation
R319 Methylation
R330 Methylation
T333 Phosphorylation
S336 Phosphorylation
T338 Phosphorylation
R344 Methylation
R365 Methylation
R373 Methylation
R381 Methylation
R388 Methylation
R402 Methylation
R405 Methylation
R423 Methylation
R428 Methylation
R458 Methylation
R463 Methylation
R468 Methylation
R475 Methylation
S480 Phosphorylation
S486 Phosphorylation
S498 Phosphorylation
R499 Methylation
T507 Phosphorylation
S518 Phosphorylation
S524 Phosphorylation
T531 Phosphorylation
S562 Phosphorylation
K567 Ubiquitination
K572 Ubiquitination

研究背景

功能:

One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs (By similarity).

细胞定位:

Nucleus.
Note: Localized with DDX1 in cleavage bodies.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

The CSTF complex is composed of CSTF1 (50 kDa subunit), CSTF2 (64 kDa subunit) and CSTF3 (77 kDa subunit). CSTF2 directly interacts with CSTF3, SYMPK and RPO2TC1. Interacts with HSF1 in heat-stressed cells. Interacts with CPSF2, CPSF3 and FIP1L1. Interacts with DDX1.

研究领域

· Genetic Information Processing > Translation > mRNA surveillance pathway.

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