JAM1 Recombinant Rabbit mAb - #BF3549

WB 1:1000, IF/ICC 1:50
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

Human

Monoclonal [ReFirm22996]

JAM1 Recombinant Rabbit mAb detects endogenous levels of JAM1.

Unconjugated.

Affinity-chromatography.

Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets,forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition,the encoded protein can act as (1) a receptor for reovirus,(2) a ligand for the integrin LFA1,involved in leukocyte transmigration,and (3) a platelet receptor. Multiple 5' alternatively spliced variants,encoding the same protein,have been identified but their biological validity has not been established.