SP1 Recombinant Rabbit mAb - #BF3512

WB 1:1000-1:3000, IHC 1:100-1:200, IF/ICC 1:100-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

Human, Mouse, Rat

Monoclonal [ReFirm22959]

SP1 Recombinant Rabbit mAb detects endogenous levels of SP1.

Unconjugated.

Affinity-chromatography.

Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes,including cell differentiation,cell growth,apoptosis,immune responses,response to DNA damage,and chromatin remodeling. Post-translational modifications such as phosphorylation,acetylation,glycosylation,and proteolytic processing significantly affect the activity of this protein,which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.