nNOS Recombinant Rabbit mAb - #BF3467

WB 1:1000, IF/ICC 1:100-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

Human, Mouse, Rat

Monoclonal [ReFirm22914]

nNOS Recombinant Rabbit mAb detects endogenous levels of nNOS.

Unconjugated.

Affinity-chromatography.

Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

The protein encoded by this gene belongs to the family of nitric oxide synthases,which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical,which acts as a biologic mediator in several processes,including neurotransmission,and antimicrobial and antitumoral activities. In the brain and peripheral nervous system,nitric oxide displays many properties of a neurotransmitter,and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases,neural regulation of smooth muscle,including peristalsis,and penile erection. This protein is ubiquitously expressed,with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally,alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.