ERCC5 Antibody - #DF3143

(1)  
产品: ERCC5 抗体
货号: DF3143
描述: Rabbit polyclonal antibody to ERCC5
应用: WB IF/ICC
反应: Human
预测: Bovine, Dog
分子量: 130 KD; 133kD(Calculated).
蛋白号: P28715
RRID: AB_2835520

浏览相似产品>>

   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

联系销售
相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Bovine(80%), Dog(80%)
克隆:
Polyclonal
特异性:
ERCC5 Antibody detects endogenous levels of total ERCC5.
RRID:
AB_2835520
引用格式: Affinity Biosciences Cat# DF3143, RRID:AB_2835520.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

COFS 3; COFS3; DNA excision repair protein ERCC 5; DNA excision repair protein ERCC-5; DNA excision repair protein ERCC5; DNA repair protein complementing XP G cells; DNA repair protein complementing XP-G cells; DNA repair protein complementing XPG cells; ERCC 5; ERCC5; ERCC5_HUMAN; ERCM 2; ERCM2; Excision repair cross complementation group 5; Excision Repair Cross Complementing Rodent Repair Deficiency; Excision repair cross complementing rodent repair deficiency complementation group 5; Excision repair protein; OTTHUMP00000064902; UVDR; Xeroderma Pigmentosum Complementation Group G; Xeroderma pigmentosum complementation group G protein; Xeroderma pigmentosum group G complementing protein; Xeroderma pigmentosum group G-complementing protein; XPG; XPG complementing protein; XPGC;

抗原和靶标

免疫原:
Uniprot:

P28715(ERCC5_HUMAN) >>Visit HPA database.

基因/基因ID:
ERCC5(2073)
序列:
MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVTCMLRKEKEAAASEIEAVSVAMEKEFELLDKAKGKTQKRGITNTLEESSSLKRKRLSDSKGKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKEKMVLVTARSVFGKKRRKLRRARGRKRKT

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Bovine
80
Dog
80
Pig
0
Horse
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P28715 作为底物

Site PTM Type Enzyme
K8 Acetylation
K8 Ubiquitination
K64 Ubiquitination
S100 Phosphorylation
K111 Ubiquitination
K120 Ubiquitination
K126 Ubiquitination
S156 Phosphorylation
S157 Phosphorylation
K172 Ubiquitination
K209 Ubiquitination
T217 Phosphorylation
K235 Ubiquitination
K240 Ubiquitination
K252 Ubiquitination
K274 Ubiquitination
Y289 Phosphorylation
K293 Ubiquitination
K298 Ubiquitination
S307 Phosphorylation
K313 Ubiquitination
S318 Phosphorylation
K322 Ubiquitination
T331 Phosphorylation
T338 Phosphorylation
S341 Phosphorylation
T344 Phosphorylation
S355 Phosphorylation
S356 Phosphorylation
S357 Phosphorylation
S363 Phosphorylation
S382 Phosphorylation
S384 Phosphorylation
S389 Phosphorylation
K392 Ubiquitination
K402 Ubiquitination
S423 Phosphorylation
S424 Phosphorylation
S428 Phosphorylation
K433 Ubiquitination
K438 Acetylation
S477 Phosphorylation
T523 Phosphorylation
S526 Phosphorylation
S558 Phosphorylation
S559 Phosphorylation
S562 Phosphorylation
S563 Phosphorylation
T567 Phosphorylation
S573 Phosphorylation
S662 Phosphorylation
S678 Phosphorylation
S699 Phosphorylation
S705 Phosphorylation
S724 Phosphorylation
T738 Phosphorylation
K751 Ubiquitination
K904 Ubiquitination
T920 Phosphorylation
T924 Phosphorylation
K952 Ubiquitination
K972 Ubiquitination
K982 Ubiquitination
S1012 Phosphorylation
T1020 Phosphorylation
S1032 Phosphorylation
K1050 Ubiquitination
S1069 Phosphorylation
K1071 Methylation
K1071 Ubiquitination
S1129 Phosphorylation
S1132 Phosphorylation
K1139 Acetylation
T1145 Phosphorylation
S1147 Phosphorylation
S1148 Phosphorylation
S1149 Phosphorylation
S1151 Phosphorylation

研究背景

功能:

Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Interacts with PCNA.

蛋白家族:

Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.

研究领域

· Genetic Information Processing > Replication and repair > Nucleotide excision repair.

限制条款

产品的规格、报价、验证数据请以官网为准，官网链接：www.affbiotech.com | www.affbiotech.cn（简体中文）| www.affbiotech.jp（日本語）

产品的数据信息为Affinity所有，未经授权不得收集Affinity官网数据或资料用于商业用途，对抄袭产品数据的行为我们将保留诉诸法律的权利。

产品相关数据会因产品批次、产品检测情况随时调整，如您已订购该产品，请以订购时随货说明书为准，否则请以官网内容为准，官网内容有改动时恕不另行通知。

Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时，请您在Affinity官方渠道提交售后申请。

产品仅供科学研究使用。不用于诊断和治疗。 

产品未经授权不得转售。

Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.