产品描述

来源:
Rabbit IgG
应用:
WB 1:1000, IHC: 1:200-1:1000, IF/ICC 1:100
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Monoclonal [ReFirm22738]
特异性:
BMAL1 Recombinant Rabbit mAb detects endogenous levels of BMAL1.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ARNT like protein 1 brain and muscle; Arntl; Aryl hydrocarbon receptor nuclear translocator like; Aryl hydrocarbon receptor nuclear translocator like protein 1; Aryl hydrocarbon receptor nuclear translocator-like protein 1; Basic helix loop helix PAS orphan MOP3; Basic helix loop helix PAS protein MOP3; Basic-helix-loop-helix-PAS protein MOP3; bHLH PAS protein JAP3; bHLH-PAS protein JAP3; bHLHe5; BMAL 1; BMAL1_HUMAN; BMAL1c; Brain and muscle ARNT like 1; Brain and muscle ARNT-like 1; CG8727 PA; Class E basic helix-loop-helix protein 5; cycle; JAP 3; JAP3; Member of PAS protein 3; Member of PAS superfamily 3; MGC47515; MOP 3; MOP3; PAS domain-containing protein 3; PASD 3; PASD3; TIC;

抗原和靶标

免疫原:

A synthetic peptide from human BMAL1

基因/基因ID:
描述:
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1,PER2,PER3) and Cryptochrome (CRY1,CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK,ARNTL complexes. Defects in this gene have been linked to infertility,problems with gluconeogenesis and lipogenesis,and altered sleep patterns. The protein regulates interferon-stimulated gene expression and is an important factor in viral infection,including COVID-19.

研究领域

· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.

· Organismal Systems > Environmental adaptation > Circadian rhythm.   (View pathway)

· Organismal Systems > Nervous system > Dopaminergic synapse.

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