DGKA Antibody - #DF3127

(6)  
产品: DGKA 抗体
货号: DF3127
描述: Rabbit polyclonal antibody to DGKA
应用: WB IHC IF/ICC
反应: Human
分子量: 80 KD; 83kD(Calculated).
蛋白号: P23743
RRID: AB_2835504

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
DGKA Antibody detects endogenous levels of total DGKA.
RRID:
AB_2835504
引用格式: Affinity Biosciences Cat# DF3127, RRID:AB_2835504.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

80 kDa diacylglycerol kinase; DAG kinase alpha; DAGK; DAGK1; DGK alpha; DGK-alpha; dgkA; DGKA_HUMAN; Diacylglycerol kinase alpha; Diacylglycerol kinase, alpha 80kDa; Diglyceride kinase alpha; MGC12821; MGC42356; OTTHUMP00000242836; OTTHUMP00000242955; OTTHUMP00000244046;

抗原和靶标

免疫原:
Uniprot:

P23743(DGKA_HUMAN) >>Visit HPA database.

基因/基因ID:
DGKA(1606)
表达:
P23743 DGKA_HUMAN:

Lymphocytes and oligodendroglial cells.

序列:
MAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAKYVQGDAIGYEGFQQFLKIYLEVDNVPRHLSLALFQSFETGHCLNETNVTKDVVCLNDVSCYFSLLEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLEMTLKDDGQHMWRPKRFPRPVYCNLCESSIGLGKQGLSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQAVGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIPQQTEEKSDPVPFQIINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPDILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKITHKNQMPMLMGPPPRSTNFFGFLS

翻译修饰 - P23743 作为底物

Site PTM Type Enzyme
K18 Ubiquitination
Y22 Phosphorylation
S23 Phosphorylation
T24 Phosphorylation
K25 Ubiquitination
K26 Ubiquitination
K32 Ubiquitination
K41 Ubiquitination
Y50 Phosphorylation
K211 Ubiquitination
Y218 Phosphorylation
K239 Ubiquitination
K249 Ubiquitination
K260 Ubiquitination
K263 Ubiquitination
Y335 Phosphorylation P06239 (LCK) , P12931 (SRC)
S348 Phosphorylation
K353 Acetylation
K353 Ubiquitination
K384 Ubiquitination
K411 Ubiquitination
K422 Ubiquitination
K484 Acetylation
K484 Ubiquitination
K487 Ubiquitination
S492 Phosphorylation
K493 Ubiquitination
K543 Ubiquitination
K547 Ubiquitination
Y623 Phosphorylation
K634 Ubiquitination
T637 Phosphorylation
K643 Ubiquitination
K652 Ubiquitination
Y669 Phosphorylation
T670 Phosphorylation
K681 Ubiquitination
K691 Ubiquitination
K714 Ubiquitination
S735 Phosphorylation

研究背景

功能:

Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity.

组织特异性:

Lymphocytes and oligodendroglial cells.

亚基结构:

Monomer.

蛋白家族:

Belongs to the eukaryotic diacylglycerol kinase family.

研究领域

· Environmental Information Processing > Signal transduction > Phosphatidylinositol signaling system.

· Environmental Information Processing > Signal transduction > Phospholipase D signaling pathway.   (View pathway)

· Human Diseases > Cancers: Overview > Choline metabolism in cancer.   (View pathway)

· Metabolism > Lipid metabolism > Glycerolipid metabolism.

· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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