产品描述

货号:
BF6125
简介:
Daclizumab (Ro 24-7375) is a humanized, monoclonal antibody that blocks CD25 (α-subunit of the high-affinity interleukin-2 receptor (IL-2R-HA)). Daclizumab inhibits effector T cell activation, regulatory T cell (Treg) expansion and survival, and activation-induced T-cell apoptosis. Daclizumab increases IL-2 bioavailability to bind to the intermediate-affinity IL-2R (IL-2R-IA), driving the expansion of anti-inflammatory CD56bright natural killer (NK) cells. Daclizumab can be used for multiple sclerosis and cancer research.
别名:

达昔单抗; Ro 24-7375

靶标:
IL-2
蛋白ID:
P01589
基因ID:
3559
分子量:
144.24 kDa
应用:
FACS, ELISA, Functional assay
反应:
Human
CAS NO.:
152923-56-3
纯度:
≥99.0%
运输方式:
Shipping with dry ice.
缓冲液:
Supplied as a 0.22 μm filtered solution in 100 mM Pro-AC, 20 mM Arg, pH 5.0
储存条件:
Store at -80°C for 2 years. Aliquots should be stored at the same temperature after first use to avoid multiple freeze-thaws.

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