Isatuximab - #BF6086
产品描述
货号:
BF6086
简介:
Isatuximab is a monoclonal antibody targeting the transmembrane receptor and ectoenzyme CD38, a protein highly expressed on hematological malignant cells, including those in multiple myeloma (MM). Isatuximab has antitumor activity via multiple biological mechanisms, including antibody-dependent cellular-mediated cytotoxicity, complement-dependent cytotoxicity, antibody-dependent cellular phagocytosis, and direct induction of apoptosis without crosslinking. Isatuximab also directly inhibits CD38 ectoenzyme activity, which is implicated in many cellular functions.
别名:
艾萨妥昔单抗; ch38SB19; hu38SB19; SAR-650984
靶标:
CD38
蛋白ID:
P28907
基因ID:
952
分子量:
145.2 kDa
应用:
FACS, ELISA, Functional assay
反应:
Human
CAS NO.:
1461640-62-9
缓冲液:
Supplied as a 0.22 μm filtered solution in isatuximab-irfc, Sucrose, histidine hydrochloride
储存条件:
Store at 4°C for 2 years, do not freeze.
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