AFfirm™ CDH19 Mouse Monoclonal Antibody - #BF9448

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产品: CDH19 小鼠 单克隆 抗体
货号: BF9448
描述: Mouse monoclonal antibody to CDH19
应用: WB
反应: Human
预测: Human, Bovine, Sheep, Dog
分子量: 87 KD; 87kD(Calculated).
蛋白号: Q9H159

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 100ul RMB¥ 1150 2300 现货

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产品描述

来源:
Mouse
应用:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Monoclonal [AFfirm9448]
特异性:
CDH19 Mouse Monoclonal Antibody detects endogenous levels of total CDH19.
偶联:
Unconjugated.
纯化:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CAD19_HUMAN; Cadherin 19, type 2; Cadherin-19; CDH 19; CDH19; CDH7; CDH7L2; PRO941; UNQ478;

抗原和靶标

免疫原:
Uniprot:

Q9H159(CAD19_HUMAN) >>Visit HPA database.

基因/基因ID:
CDH19(28513)
表达:
Q9H159 CAD19_HUMAN:

Expressed in many tissues, with the exception of uterus.

序列:
MNCYLLLRFMLGIPLLWPCLGATENSQTKKVKQPVRSHLRVKRGWVWNQFFVPEEMNTTSHHIGQLRSDLDNGNNSFQYKLLGAGAGSTFIIDERTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDINDNEPKFLDEPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQPYFSVEPTTGVIRISSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRLTVSESAPTGTSIGTIMAYDNDIGENAEMDYSIEEDDSQTFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFEETPQGSFVGVVSATDPDNRKSPIRYSITRSKVFNINDNGTITTSNSLDREISAWYNLSITATEKYNIEQISSIPLYVQVLNINDHAPEFSQYYETYVCENAGSGQVIQTISAVDRDESIEEHHFYFNLSVEDTNNSSFTIIDNQDNTAVILTNRTGFNLQEEPVFYISILIADNGIPSLTSTNTLTIHVCDCGDSGSTQTCQYQELVLSMGFKTEVIIAILICIMIIFGFIFLTLGLKQRRKQILFPEKSEDFRENIFQYDDEGGGEEDTEAFDIAELRSSTIMRERKTRKTTSAEIRSLYRQSLQVGPDSAIFRKFILEKLEEANTDPCAPPFDSLQTYAFEGTGSLAGSLSSLESAVSDQDESYDYLNELGPRFKRLACMFGSAVQSNN

翻译修饰 - Q9H159 作为底物

Site PTM Type Enzyme
Y4 Phosphorylation
S111 Phosphorylation
Y113 Phosphorylation
S402 Phosphorylation
S407 Phosphorylation
T409 Phosphorylation
K623 Acetylation
K630 Acetylation
K630 Ubiquitination
S631 Phosphorylation
S685 Phosphorylation
S692 Phosphorylation

研究背景

功能:

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

细胞定位:

Cell membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in many tissues, with the exception of uterus.

蛋白家族:

Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.

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