产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
H7; Na(+)/H(+) exchanger 2; NHE 2; NHE-2; NHE2; SL9A2_HUMAN; Slc9a2; Sodium/hydrogen exchanger; Sodium/hydrogen exchanger 2; Solute carrier family 9 (sodium/hydrogen exchanger), member 2; Solute carrier family 9 member 2; Solute carrier family 9, member 2;
抗原和靶标
Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine.
- Q9UBY0 SL9A2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPLGNWRSLRAPLPPMLLLLLLQVAGPVGALAETLLNAPRAMGTSSSPPSPASVVAPGTTLFEESRLPVFTLDYPHVQIPFEITLWILLASLAKIGFHLYHKLPTIVPESCLLIMVGLLLGGIIFGVDEKSPPAMKTDVFFLYLLPPIVLDAGYFMPTRPFFENIGTIFWYAVVGTLWNSIGIGVSLFGICQIEAFGLSDITLLQNLLFGSLISAVDPVAVLAVFENIHVNEQLYILVFGESLLNDAVTVVLYNLFKSFCQMKTIETIDVFAGIANFFVVGIGGVLIGIFLGFIAAFTTRFTHNIRVIEPLFVFLYSYLSYITAEMFHLSGIMAITACAMTMNKYVEENVSQKSYTTIKYFMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFVCFTLAFCLMWRALGVFVLTQVINRFRTIPLTFKDQFIIAYGGLRGAICFALVFLLPAAVFPRKKLFITAAIVVIFFTVFILGITIRPLVEFLDVKRSNKKQQAVSEEIYCRLFDHVKTGIEDVCGHWGHNFWRDKFKKFDDKYLRKLLIRENQPKSSIVSLYKKLEIKHAIEMAETGMISTVPTFASLNDCREEKIRKVTSSETDEIRELLSRNLYQIRQRTLSYNRHSLTADTSERQAKEILIRRRHSLRESIRKDSSLNREHRASTSTSRYLSLPKNTKLPEKLQKRRTISIADGNSSDSDADAGTTVLNLQPRARRFLPEQFSKKSPQSYKMEWKNEVDVDSGRDMPSTPPTPHSREKGTQTSGLLQQPLLSKDQSGSEREDSLTEGIPPKPPPRLVWRASEPGSRKARFGSEKP
翻译修饰 - Q9UBY0 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y356 | Phosphorylation | Uniprot | |
| Y361 | Phosphorylation | Uniprot | |
| S499 | Phosphorylation | Uniprot | |
| Y503 | Phosphorylation | Uniprot | |
| K536 | Ubiquitination | Uniprot | |
| S551 | Phosphorylation | Uniprot | |
| Y610 | Phosphorylation | Uniprot | |
| S623 | Phosphorylation | Uniprot | |
| S643 | Phosphorylation | Uniprot | |
| S647 | Phosphorylation | Uniprot | |
| S652 | Phosphorylation | Uniprot | |
| S661 | Phosphorylation | Uniprot | |
| T662 | Phosphorylation | Uniprot | |
| S665 | Phosphorylation | Uniprot | |
| Y667 | Phosphorylation | Uniprot | |
| S669 | Phosphorylation | Uniprot | |
| T674 | Phosphorylation | Uniprot | |
| K679 | Acetylation | Uniprot | |
| S739 | Phosphorylation | Uniprot | |
| S745 | Phosphorylation | Uniprot | |
| T746 | Phosphorylation | Uniprot | |
| T749 | Phosphorylation | Uniprot | |
| S752 | Phosphorylation | Uniprot | |
| T757 | Phosphorylation | Uniprot |
研究背景
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.
Phosphorylated (Possible).
Membrane>Multi-pass membrane protein.
Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine.
Interacts with CHP1 and CHP2.
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
限制条款
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