产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
B cell CLL/lymphoma 7 protein family member B; B cell CLL/lymphoma 7B; B-cell CLL/lymphoma 7 protein family member B; BCL 7B; BCL7B; BCL7B_HUMAN;
抗原和靶标
- Q9BQE9 BCL7B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKSKSNSSAAREPNGFPSDASANSSLLLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQSESLSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDSGAPPLKRFCVDQPTVPQTASES
翻译修饰 - Q9BQE9 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K27 | Ubiquitination | Uniprot | |
| K34 | Ubiquitination | Uniprot | |
| T41 | Phosphorylation | Uniprot | |
| S107 | Phosphorylation | Uniprot | |
| S108 | Phosphorylation | Uniprot | |
| T109 | Phosphorylation | Uniprot | |
| S112 | Phosphorylation | Uniprot | |
| S114 | Phosphorylation | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| S120 | Phosphorylation | Uniprot | |
| S122 | Phosphorylation | Uniprot | |
| T126 | Phosphorylation | Uniprot | |
| S127 | Phosphorylation | Uniprot | |
| T131 | Phosphorylation | Uniprot | |
| S134 | Phosphorylation | Uniprot | |
| S180 | Phosphorylation | Uniprot | |
| K186 | Ubiquitination | Uniprot | |
| C189 | S-Nitrosylation | Uniprot | |
| T194 | Phosphorylation | Uniprot | |
| S200 | Phosphorylation | Uniprot |
研究背景
Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1. Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation. May play a role in lung tumor development or progression (By similarity).
Ubiquitous.
Belongs to the BCL7 family.
限制条款
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