TIMP2 Antibody - #AF7008

Figure 4 The effect of exposure of pregnant Wistar rat dams to fumonisins on COMP, VEGF, MMP-8, OPG, RANKL and TIMP-2 protein expression in female (a) and male (b) offspring femora. The protein levels are normalized to the corresponding β-actin levels and expressed as the fold change relative to the amount present in 0 FB control group. 0 FB—the control group; 60 FB—the group of offspring of pregnant rats receiving during pregnancy fumonisins at the dose of 60 FB/kg b.w.; 90 FB—the group of offspring of pregnant rats receiving during pregnancy fumonisins at the dose of 90 FB/kg b.w. Data are mean values ± SD (n = 3). Uncropped original Western blot membranes can be found in Supplementary Figure S1. Statistical significance

Figure 2 Expression of lumican, MMP-2, MMP-14 and TIMP-2 in scleral tissue. Expression levels of lumican, MMP-2, MMP-14 and TIMP-2 expression at the (A) mRNA and (B) protein levels, detected by reverse transcription-quantitative PCR and western blotting, respectively. (C) Immunohistochemical analysis of lumican, MMP-2, MMP-14 and TIMP-2 expression. (D) Quantification of results presented in panel C. *P<0.05 vs. control eyes (paired t-tests). TIMP, tissue inhibitor of metalloproteinases.

Figure 5 MMP-2, MMP-14 and TIMP-2 expression in rat scleral fibroblasts following lumican overexpression or knockdown. *P<0.05 vs. the control group (one-way ANOVA and Tukey's post hoc tests). TIMP, tissue inhibitor of metalloproteinases.

Figure 2. |Expression of lumican, MMP‑2, MMP‑14 and TIMP‑2 in scleral tissue. (C) Immunohistochemical analysis of lumican, MMP‑2, MMP‑14 and TIMP‑2 expression.