产品: DUSP18 抗体
货号: DF15790
描述: Rabbit polyclonal antibody to DUSP18
应用: ELISA(peptide)
反应: Human, Rat
分子量: 21kD(Calculated).
蛋白号: Q8NEJ0

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 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Rat
克隆:
Polyclonal
特异性:
DUSP18 Antibody detects endogenous levels of DUSP18.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Dual specificity protein phosphatase 18; DUS18_HUMAN; Dusp18; LMW-DSP20; LMWDSP20; Low molecular weight dual specificity phosphatase 20;

抗原和靶标

免疫原:

A synthesized peptide derived from human DUSP18.

Uniprot:
基因/基因ID:
表达:
Q8NEJ0 DUS18_HUMAN:

Widely expressed with highest levels in liver, brain, ovary and testis.

序列:
MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEKEVRLMIPL

研究背景

功能:

Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP).

细胞定位:

Cytoplasm. Nucleus. Mitochondrion inner membrane>Peripheral membrane protein>Intermembrane side.
Note: Translocates to cytoplasm in response to apoptotic stimuli such as staurosporine treatment.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Widely expressed with highest levels in liver, brain, ovary and testis.

蛋白家族:

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

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