| 产品: | WDYHV1 抗体 |
| 货号: | DF15786 |
| 描述: | Rabbit polyclonal antibody to WDYHV1 |
| 应用: | ELISA(peptide) |
| 反应: | Human, Mouse, Rat |
| 分子量: | 24kD(Calculated). |
| 蛋白号: | Q96HA8 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
C8orf32; Chromosome 8 open reading frame 32; FLJ10204; N terminal Gln amidase; Nt(Q) amidase; Protein N terminal glutamine amidohydrolase; Protein NH2 terminal glutamine deamidase; WDYHV motif containing 1; WDYHV motif containing protein 1;
抗原和靶标
A synthesized peptide derived from human WDYHV1.
- Q96HA8 NTAQ1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEGNGPAAVHYQPASPPRDACVYSSCYCEENIWKLCEYIKNHDQYPLEECYAVFISNERKMIPIWKQQARPGDGPVIWDYHVVLLHVSSGGQNFIYDLDTVLPFPCLFDTYVEDAFKSDDDIHPQFRRKFRVIRADSYLKNFASDRSHMKDSSGNWREPPPPYPCIETGDSKMNLNDFISMDPKVGWGAVYTLSEFTHRFGSKNC
研究背景
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
Cytoplasm>Cytosol. Nucleus.
Monomer.
Belongs to the NTAQ1 family.
限制条款
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